Mapiritsiti eSiofor inogadzirwa nemishonga inogadzirirwa varwere vane chirwere cheshuga mellitus . Icho chiri cheboka guru remishonga inonzi biguanide. Kushandisa mushonga waro wemazuva ano wakadzidza kwete kwete chete kurapwa, asiwo nekubvisa kuwedzera kwehutano.
Kuumbwa kwehwendefa Siofor
Inobva pane metformin. Izvi zvinoshandisa glycogen synthetase, izvo zvinoita kuti kuve nekutanga kwe intracellular glycogen kushandiswa. Somugumisiro, kutakura kwemaitiro emapurotini emaglocose kunowedzera zvakanyanya, kuwanda kwehushuterolini inoderera, uye mafuta anonzi metabolism anozivikanwa.
Pakati pezvakagadzirwa mumapiritsi kubva kune shuga daiobet Siofor zvinhu zvakadai se:
- povidone;
- titanium dioxide;
- macrogol;
- magnesium stearate;
- hypromellose.
Kushandiswa kweSiofor
Somugumisiro wekutora mishonga, basal uye postpandial glucose concentrations inowedzera. Kutenda kune chivako ichi, mahwendefa eSiofor akabatwawo nechipiri chechirwere cheshuga mellitus. Chokutanga, mushonga unorayirwa kune varwere vanotambura nokurema kwakanyanya, izvo zvisingagoni kurapwa nezvikafu kana zvemitambo.
Siofor inobatsira kuderedza kuwanda kweglucose yakagadzirwa uye kuwedzera kuvanzwa kwemisungo kune chiito che insulin, kuitira kuti shuga inokurumidza kubviswa mumuviri.
Tora Siofor mahwendefa kubva muchirudzi chechirwere cheshuga chinogona kushandiswa se monotherapy, uye pamwe chete nemimwe mishonga. Nhamba yekutanga inowanzotora 500 mg kaviri zuva rimwe nerimwe kana 850 mg kamwe.
Kupindirana kwekushandiswa kweSiofor
Iwe haugoni kunwa Siofor vana kusvika pazera remakore gumi, pamwe chete nevaya vanotambura nekuwedzera kwekunzwisisika kusvika kune metformin uye zvimwe zvikamu zvepiritsi. Mukuwedzera, mushonga unopesana apo apo:
- pamuviri;
- renal failure ;
- hepatic insufficiency;
- zvirwere zvakakomba, zvinotungamirira ku hypo hypoia yematukisi.