Chirwere (squamous) metaplasia chirwere chisina kenza mu epithelium chemukati, izvo zvinodzivirirwa zvemuviri kune simba rezvinhu zvisingafadzi. Metaplasia inzira inoratidzika mune imwe nzira iyo imwe-yakavezwa yakagadzika, chirmatic kana cubic epithelium inoshandiswa nemamwe masero akaoma emagetsi akawanda eplainium, kana pasina keratinini. Kazhinji kacho kazhinji kacho kemukari metaplasia inokanganisa mapapurilium epapaulium (kunyanya kune vanhu vanoputa) uye chirwere chechivharo, asi chinogona kukanganisa mucosa yemukaka, matumbo, mukati mezvinyorwa.
The mechanism of squamous cell metaplasia
Kubudirira kwemasaplasia, tinofunga muenzaniso wechirwere chinonzi mucous, apo kushandiswa kweplindrical epithelium yakazara. I-metaplastic flat epithelium haigoni kubva kumasero anokwana masimba, asi kubva pasi, izvo zvinonzi zvinodzivirira masero. Icho chikonzero, pasi pechipfuva cheplinylum epithelium, nzvimbo yakachengetwa masero inoumbwa, iyo inokura zvishoma nezvishoma. Zvishoma nezvishoma, chikamu chepamusoro cheplinylum epithelium chinodonhedzwa uye chinogadziriswa chinoitika. Inotevera inouya nheyo yekusanganisa squamous cell metaplasia, umo zvidzidzo zvestologi zvinoratidzika zvakajeka kumiganhu yemapoka echengeterwa masero uye kuumba zvikamu zvakasiyana-siyana zvemasero akafanana neaigara pamba pasina-coronary epithelium.
Pachitambo chekukura squamous cell metaplasia, masero anowedzera uye akafanana akafanana nemasero epakati epa epithelium flat, uye pachikwata chemasaplasia yakakura, epithelium haisi kusanzwisisiki kubva kune zvisikwa zvepasi pane epithelium flat.
Inonzi squamous metaplasia inotyisa here?
Metaplasia haisi chirwere, asi zvakasiyana-siyana zvehupenyu zvinoshandiswa kuhupenyu hwepanyama kana hutano hwepfungwa zvinokonzera. Nezveiyo nyaya chaiyo, squamous cell metaplasia haisi uye inowanikwa muongorori dzeongororo, nekuda kwekuonekwa kwemasero epa epithelium flat mu smears, sputum, zvimwe zvekutsvakurudza kana histological test of tissues.
Kazhinji kazhinji, metaplasia inoumbwa kunopesana nemamiriro ekusava nekuputika kwezvirongwa, pamwe chete nekunze kwezvinhu zvinokanganisa (kusvuta, kushanda munzvimbo isina kunaka, nezvimwewo). Kunyange zvazvo pachechi iyo inenge iine hutachiona, yakashandurwa, asi kushivirira kwenguva refu kwezvinhu zvakashata kana kusavapo kwechirwere chechirwere chinokonzera kuchinja, chinogona kuenderera mberi ku dysplasia uye chisina kumira mamiriro ezvinhu.
Zvinokonzera uye kurapa kwe squamous metaplasia
Chinozivikanwa ndeye squamous metaplasia yemukati. Inogona kuitika kune:
- chisingagumi kupera;
- kudengenyeka kwemukati ;
- hormonal disorders;
- zvirwere zvinotapukira.
Squamous cell lung metaplasia inowanzokonzerwa nekusvuta, asi inogona kukonzerwa nezvirwere zvisingaperi (bronchitis, asthma , etc.). Metaplasia yebladder inokonzerwa nekuputira zvirongwa, uye panzvimbo yekutanga pakati pezvikonzero ndizvo cystitis.
Sezvo squamous cell metaplasia inopesana nemagadzirirwo anoita muviri, hazvirevi kurapwa kwakananga. Mushure mokurapa chirwere chepachivi kana kupera kwemaitiro emuviri wepfungwa, shure kwechinguva epithelium pachayo inodzokera kune yakajairika. Somuenzaniso, kurapa squamous cell metaplasia ye-bronchial epithelium, yakashungurudzwa nekusvuta, zvakakwana kusiya tsika iyi, uye zororo rose richava chiratidzo.