MAO inhibitors

MAO inhibitors ndeyezvinhu zvinokonzerwa nehupenyu hunoita kuti kuwedzerwa kuwedzerwa kwemaitiro emagunha. Mishonga iyi inangwa yekurapa zvimwe zvinetso zvekutya, kuora mwoyo, narcolepsy uye chirwere chaPasinson .

MAO inhibitors - chii chinovanetsa?

Nezvemishonga yavo yemishonga, madhiragi aya akaparadzaniswa kuva marudzi mazhinji:

1. Kwete-selective irreversible inhibitors, iyo yakafanana zvakanyanya mukugadzirwa kweproniazides. Vanoderedza nhamba yekurwiswa kwema angina, uyewo vanoita kuti munhu arege kuora mwoyo.
2. Zvisarudzo zvinoshandiswa zvinoshandiswa zvinotarisirwa kubvisa kukanganiswa kweyodadrenaline uye serotonin. Iyi mishonga ine simba rinopesana nemanzwiro.
3. Mishonga isingakanganwiki inoshandiswa inoshandiswa kurapa chirwere chePalinson. Zvinonyatsobatanidzwa mune metabolism ye catecholamines uye dopamine.

MAO inhibitors - urongwa hwezvinodhaka

Zvisingasarudze Zvinodhaka Zvisingabvumirwi

1. Ipronizade. Mushonga weboka revarwere vanodzvinyirira. Icho chinokonzerwa nehepatotoxic effect - inokuvadza chiropa chomunhu.
2. Nialamide. Ichi chinonzi antidipressant. Pfupa yakaisvonaka yemuchena mutsvuku nekatsvuku tinge tinge. Inonyatsosvibiswa mumvura, uye mune doro - kunyanya kuipa. Mushonga unorambidzwa kuvanhu vane chiropa, zvinetso, moyo yematambudziko. Izvowo haifaniri kushandiswa nevanhu vane utano husina simba hwekupararira kwepfungwa.
3. Isocarboxazide. Inowanzoshandiswa kugadzirisa kuora mwoyo uye kunonoka. Kufanana nemimwe mishonga boka rinogona kukuvadza chiropa, itsvo nemoyo.
4. Fenelzin. Inotorwa kunatsiridza mamiriro ezvinhu ose. Inonyanya kushandiswa sevanorwisa mweya.
5. Tranylcypromine. Mushonga uyu wakagadzirirwawo kutarisana nekuora mwoyo. Inofungidzirwa ichikurudzira. Muchikamu chinoshingaira, sendimiti inopfuurira kuenda kuAmphetamine. Vamwe varwere vanogona kunge vaine chivimbo pane zvinoita kuti vanhu vaite simba.

Rwendo rwekusarudzira reversible drugs-MAO inhibitors

1. Bethol. Iko kunonzi inodhaka mwoyo. Ane antireserpine chiito. Izvozvo zvinokonzerwa nehuwandu hwe phenamine inopiwa.
2. MacLobemide. Mushonga unoratidzira kuvhiringidzika. Iyo yakarongeka yakafanana neyo, asi inenge iine musiyano mumatomu mashoma. Munguva yekugamuchira, yakaoma mucous membrane, kurwadziwa mumusoro, kusuruvara, kurara, kana zvimwe zvinogona kuitika. Mune zvimwe zviitiko kuvhiringidzika, zvinetso zvemudumbu, kusvibiswa kwemaviri uye kuora mwoyo kwechinguva zvakaonekwa. Varwere vane bipolar kushushikana kazhinji vaiva nechinhanho chechikamu mania.
3. Pyrazidol. Basa rayo rakafanana neInkazan neTetrindol. Icho chinhu chinoita kuti vanhu vave nehanya nekunetseka. Icho chinogumbura. Inovandudza masimba ekugogodza. Icho chinomira pakati pevamwe nekuda kwekugona kwekutungamirira simba pamutemo weshe.
4. Inkazan. Iye zvakare metralindol. Inotorwa sekugadzirira kwepakutanga. Inoshandiswa mukugadzirwa kweschizophrenia, manic psychosis kana kuti kurapwa kwezvirwere zvevascular zveuropi. Iyo inoratidzirwa nokuda kwechirongwa chekushongedza uye chemafatic, kuvhara, uye mamiriro nemafungiro asina kunaka e hypocondriacal. Inowanzoshandiswa kurapa kuora mwoyo mune varwere vane doro.

Ndezvipi zvinodhaka zvinorongwa sechisarudzo chisingaoneki MAO inhibitors?

1. Selegiline. Chirwere ichi, chine chiito chinotungamirirwa mukurapa chirwere chePasinson uye zvigadzirwa zve syndromes, zvichikonzerwa nekushaya dopamine.
2. Razagilin. Uyu mushonga ndewechizvarwa chitsva chemishonga. Inorwisana nechiratidzo chePacinsinsonism, kunyanya nematambudziko mashoma emagetsi. Inowanzoshandiswa nemamwe madhiragi eboka racho.