Chirwere cheshuga nephropathy inonetsa yekuchinja kwehutachiona mumidziyo yeropa yeiyo itsvo inowanikwa mumarudzi maviri evanhu vane chirwere cheshuga cheshuga. Izvi zvinoratidzirwa mune anenge 10-20% yevarwere vane chirwere cheshuga cheshuga.
Zvinokonzera chirwere cheshuga nephropathy
Zvimwe zvikonzero zvinokonzera kukura kwechirwere, iyo hyperglycemia (shuga yepamusoro yeropa) uye kwenguva refu isina kukwana kubhadhara kwekuputsika kwemakinhydrate metabolism. Somugumisiro weizvi, hupenyu hwehupenyu hunochinja zvishoma nezvishoma: kutyora kwemvura-electrolyte homeostasis, kuchinjwa kwemafuta acids, kuderera kwekutakura oksijeni,
Glucose inoshandiswa kutyisa pamasero eitsvo, uyewo inoshandisa nzira dzinokonzera kukanganisa uye kuwedzera kukwana kwemasvingo avo. Pamusana pekuvhiringidza kwehutachiona hwehutachiwana hwehushuga hwemashuga, mishonga yemaperembudzi inowedzera simba, uye midziyo yakakanganiswa inotsiviwa nemagetsi anogadzirisa. Uyewo, chikamu mukurudzirwa kwechirwere cheshuga chirwere chinokonzerwa nehutachiona hwehutachiona uye kusagadzikana kwehutachiona hwehutachiona, pamwe chete neine genetic factor.
Zviratidzo uye zvikamu zvechirwere cheshuga nephropathy
Mukufambisa kwezvinetso izvi, zvikamu zvishanu zvinoratidzika, zvitatu zvaro zvinononoka, i.e. Chirwere cheshuga nephropathy pakutanga hachina zviratidzo zvekunze uye zvinongogadziriswa nedzimwe nzira dzekuraira dzakakosha kana nedhiopsy. Kunyange zvakadaro, kuonekwa kwehutachiwana muzvikamu zvekutanga kunokosha zvikuru, nokuti Iko chete munguva ino inenge ichishandurwa zvakare. Ngationgororei zvakadzama kuti kuchinjwa kunowanikwa pachikamu chimwe nechimwe chechirwere.
Nhanho I - yakawedzera masero emasero emasero, yakanyanya kuwedzerwa uye kucheneswa kwemuti (hyperfunction yezvikamu).
Chikamu chechipiri - chinoitika anenge makore 2 mushure mokutanga kwechirwere cheshuga. Kuoma kwemasvingo emidziyo yemasango kunoratidza.
Nhanho yechitatu - yakakura kukuvadza kwemidziyo yeimpimpano, microalbuminuria (chidimbu cheprotini mumuguta), kuchinja mu glomerular filtration rate.
IV nhanho -inoitika makore gumi kusvika ku15 mushure mokutanga kwechirwere cheshuga. Unhu hunhu huri:
- proteinuria (kugoverwa kwepurogiramu yakawanda yeprotini mumuguta);
- kusuruvara kwakanyanya mumakumbo, chiso, mimba yemimba, nezvimwe;;
- kuyerwa kwemuviri;
- kushaya simba;
- nausea;
- nyota;
- kazhinji misoro ;
- kuwedzerwa kweropa.
V vheji - inenge yakakwana kupera vascular sclerosis, kuderera kukuru mumabasa ekugadzirisa uye ekugadzirisa kwetsvo. Zvimwe zviratidzo ndezvi:
- massive proteinuria;
- kukura kwekushaya ropa;
- kurira kukuru;
- kuderedza hyperglycemia;
- dyspeptic syndrome;
- uremia, nezvimwewo.
Nzira yekurapa chirwere cheshuga nephropathy?
Mukurapa kwehutano, kune zvikamu zvitatu zvakakosha:
- kuchengetedza yakakwana yehuga muropa;
- Therapy ye arterial hypertension ne microalbuminuria;
- kudzivirirwa kwekukurumidzika kwekukurumidza kwebasa repso uye kukurudzirwa kwechikwata cheuyuric chekushaya simba;
- detoxification therapy.
Mukurapa kwechirwere cheshuga nephropathy, kushandiswa kwemapoka aya emishonga kunoratidzwa:
- hypoglycemic preparations;
- inhibitors ye-angiotensin-kuchinja enzyme;
- angiotensin receptor antagonists;
- beta-blockers;
- calcium channel blockers;
- Kugadzirira kwemaitiro ehutachiona eropa;
- diuretics ;
- varoyi;
- antizotemics nevamwe.
Zvinoda kuteererwa nemaitiro ekuderera-mapuroteni uye asina munyu, kuderedza kushandiswa kwemafuta. Kana chirwere chepfungwa chinoputsika zvakanyanya, zvinoita kuti utungamirire kudzokera kunorapwa (hemodialysis, zvachose peritoneal dialysis) kana kurapwa kwakagadzirwa nemupiro weiyo kupora.