Penicillins iboka remishonga inorwisa mabhakitiriya inogadzirwa nemhando yehutu hwemhando yePenicillium. Ivo vari kushingaira kurwisa bhakiticidal chiito paGr-positive, uyewo mamwe majekiseni e gram-negative. Mishonga inorwisa mabhakitiriya emutsara wepenicillin inosanganisira kwete mashizha chete, asiwo semisynthetic.
Properties:
- Mhando dzakasiyana dzematare anoshanda.
- Low toxic effects on the body.
- Zvizhinji zvekuita.
- Muchinjikwa-kune mamwe marudzi epenicillin.
- Kukurumidza kunwa uye kugoverwa mumuviri.
- Kupindira kwakanaka muzviviri, muviri wemvura.
- Kufambira mberi kwekubudirira kwerapeutic concentration.
- Kukurumidza kubviswa kubva mumuviri.
Kusarudzwa
Mishonga inorwisa mabhakitiriya eboka repenicillin, nekuda kwekunyorera kwayo, ndiyo yakanyatsorambidzwa bhaktericidal mazano. Zvisingabatsiri migumisiro inongowanikwa chete kana kune hypersensitivity kana kuti kushaya penicillin. Zvinosuruvarisa, kugadzikana kwakadaro kunowanikwa muhuwandu hwevanhu (kusvika kusvika 10%) uye hahuparidzire kumishonga chete, asiwo kune imwe mimwe michina uye zvipfeko zvine antibiotic. Chirwere chepenicillin chinokwanisika pakugamuchirwa mumuviri wepi zvayo, kunyange chidiki chiduku chechirwere. Nokudaro, ne hypersensitivity uye zvinokonzerwa nezvinokonzerwa nemararamiro zvakakosha kusarudza mishonga inorwisa mabhakitiriya pasina penicillin uye manzwiro epenicillin asina mhando yemishonga.
Mhando yemagazini
Mishonga inorwisa mabhakitiriya penicillin mutsara inowanika mumapiritsi:
- Penicillin-ekormoline mahwendefa ezvo resorption.
- Penicillin-ekormoline mahwendefa emuromo.
- Penicillin mapiritsi ne sodium citrate.
Poda inoshandiswawo kugadzirira sarudzo uye majekiseni.
Kurongwa
Mishonga inorwisa mabhakitiriya eboka re penicillin ine marudzi anotevera:
- Penicillin yepanyama - inowanikwa kubva kune zvakasikwa iyo penicillin fungi inokura.
- Biosynthetic penicillin - inowanikwa kuburikidza nehupenyu hwehutano.
- Semisynthetic penicillin - inowanikwa pamusana weAic acid yakasununguka kubva kuenhengo dzepenicillin (antibiotics inobva penicillin).
Nzvimbo dzekushanda:
Mishonga inorwisa mabhakitiriria inonzi penicillin inobatanidza zvakanyanya uye inokanganisa mabhakitiriya akaita kuti kutanga kwechirwere ichi:
- hutachiwana hwepamusoro nepamusoro pekufuridzirwa kwepamusoro;
- zvirwere zvepamuviri;
- urinary tract infection;
- zvirwere zveveereal;
- ophthalmologic maitiro.
Zvikanganiso
Pasinei nekurerukirwa kwakanaka, maantibayoti kubva muboka repenicillin anokwanisa kuva nemigumisiro inotevera pamuviri:
1. Kurwisa kweAirgic uye hypersensitivity:
- dermatitis;
- ruvara rweganda;
- kuzvimba kwemukasi membrane;
- kukundwa kwemagetsi ekugadzirisa;
- arthritis;
- spasm of bronchi;
- anaphylactic shock;
- edema yeuropi;
- arthralgia.
2. Kuchinja kwezvinotyisa:
- nausea;
- diarrhea;
- stomatitis;
- glossitis;
- necrosis yemasumbu;
- candidiasis yemuromo uye yemudzimai cavity;
- kukurudzirwa kwemasimba ekudzivirira;
- intestinal dysbiosis;
- thrombophlebitis.
3. Maitiro eurourotoxic:
- hallucinations;
- kunetseka;
- delirium;
- kukanganisa kweropa rekushandisa mutemo.
4. Kuita zvakananga:
- nzvimbo inopinda;
- zvinetso zvevascular system (One and Nicolau syndromes).
Kusvikira ikozvino, kurapwa ne penicillin imwe yenzira dzinoshanda zvikuru dzokurwisa zvirwere zvinotapukira. Asi kusarudzwa kwake kunofanira kunge kuchiitwa nechiremba maererano nekuongorora nekuongororwa kwezvinhu zvose.