Zvirwere zvinokonzera zvirwere uye mabhakitiriya ndizvo zvinokonzera zvirwere zvakakomba zvekufema, urrogenital system uye zvimwe zvikamu zvemuviri. Fluoroquinolones yerudzi rwemazuva ano zvakakunakira. Aya antimicrobial drugs anokwanisa kukunda kunyange zvirwere zvinopesana ne quinolones uye fluoroquinolones, yakashandiswa makore akawanda apfuura.
Fluoroquinolones 4 zvizvarwa - rudzii rwemishonga?
Fluoroquinolones yakashandiswa kudzora microbes kubvira kuma1960, panguva iyo mabhakitiriya akaonekwa akazvidzivirira kune mazhinji emishonga iyi. Ndicho chikonzero masayendisiti haasi kumira ipapo uye anogadzira mishonga nemishonga mitsva, achiwedzera kubudirira kwavo. Heino mazita ekupedzisira chizvarwa fluoroquinolones nevatungamiri vavo:
- Kugadzirira kwechizvarwa chekutanga (nalidixic acid, oxolinic acid).
- Chipiri-chizvarwa chemishonga (lomefloxacin, norfloxacin, ofloxacin, pefloxacin, iprofloxacin).
- Kugadzirira kwezera rechitatu (levofloxacin, parfloxacin).
- Kugadzirira kwechizvarwa chechina (moxifloxacin, hemifloxacin, gatifloxacin, sitafloxacin, trovafloxacin).
Chiito chechizvarwa chitsva che fluoroquinolones chinoenderana nekubatanidzwa kwavo muDNA yebhakitiriya, umo michina inorasikirwa nekwanisi yekuwedzera nekukurumidza kufa. Nechizvarwa chimwe nechimwe, nhamba ye bacilli inopikisana nemishonga inobatsira inowedzera. Kusvika iye zvino, izvi ndezvi:
- E. coli;
- Pseudomonas aeruginosa ;
- gnofilnaya tsvimbo;
- shigella;
- salmonella;
- cholera stick;
- hominococci;
- meningococci;
- Campylobacter;
- chlamydia;
- mycoplasma;
- pneumococci;
- staphylococci .
Hazvishamisi kuti vazhinji fluoroquinolones vari pane urongwa hwemishonga inokosha uye inonyanya kukosha - kunze kwavo hazvibviri kurapa pneumonia, kora, tuberculosis nezvimwe zvirwere zvinotyisa. Izvo zvipembenene chete izvo rudzi urwu rwemishonga harukwanisi kuchinja ndeye dzose vanaerobic mabhakitiriya.
Chii chinonzi fluoroquinolones mu mahwendefa?
Kusvika iye zvino, mahwendefa anotumirwa kuporesa fluoroquinolones kurwisa zvirwere zvepamusoro nepamusoro pekupemha, mishonga yekurapa zvirwere zvejito-urinary uye
- Levofloxacin;
- Moxifloxacin;
- Sparfloxacin;
- Norfloxacin nevamwe.
Usati watanga kurapwa, nyatsoongorora zvinopesana-zvinodhaka zvakawanda zveboka iri hazvikurudzirwi kuti zvishandiswe mukuputsa zvirwere zvakanyanya, zvinetso zvepfungwa uye chiropa. Kuvana nevakadzi vane pamuviri, fluoroquinolones inoratidzirwa zvakakwana maererano nechirongwa chechiremba pazvinouya pakuchengetedza hupenyu.