Rimwe remishonga inonyanyozivikanwa uye inoshanda yakawanda inonzi Ceftriaxone, iyo ine migumisiro inofanira kuongororwa sezvinyatsoratidzwa sezvinoratidzwa zviratidzo zvisati zvashandiswa. Chimbofunga kuti chii chinofanira kutevedzwa panguva yekurapa neyi antimicrobial agent.
Migumisiro Yechikamu yeCeftriaxone
Kunyanya kwechirwere ichi chinogona kuendeswa nehutano hwehutachiona, huno: urticaria, itching uye kuputika. Muzviitiko zvisingawanzoitiki, kune exudative erythema multiforme, bronchospasm kana kunyange anaphylactic inotyisa.
Nhengo dzemazino dzinogona kupindura pakutora mishonga nehurwere kana zvimwe zvinosvibiswa nekudzivirira, pamwe nekunyunyuta, kuputsa kwekunzwa kwekutora. Dzimwe nguva migumisiro yechirwere remishonga inonzi Ceftriaxone inoratidzwa nenzira ye glossitis (kuputira rurimi) kana stomatitis (maronda anorwadza pamuromo mucosa). Varwere vanogona kunyunyuta pamusoro pemarwadzo emimba (ane unhu husingaperi).
Kunyanya, chiropa chinopinda kune ceftriaxone: zvirwere zvayo zvinogona kuwedzera basa, pamwe nealkaline phosphatase kana bilirubin. Mune zvimwe zviitiko, zvinokwanisika kukura pseudocholithiasis ye gallbladder kana cholestatic jaundice.
Kuchinja kwephipi
Maererano nemirayiridzo, migumisiro yeCeftriaxone inogona kusanganisira kutyora kwetsvo, nekuda kwokuti ropa rinowedzera sei:
- nitrogenous metabolic products (azotemia);
- creatinine (hypercreatininaemia);
- urea.
Mumuti, pamwewo, pangavapo:
- glucose (glucosuria);
- ropa (hematuria);
- izvo zvinonzi magadziri - zvipembenene zvepuroteni kana zvikamu zvemagetsi (cylindruria).
Nhamba yemukaka yakavanzwa neitsvo inogona kuderedza (oliguria) kana kusvika kune zero mark (anuria).
Mhinduro ye hematopoietic system
Pazvikamu zvekusika kweropa, majekiseni eCeftriaxone anogona kupawo migumisiro yechirwere, iyo inosanganisira kuderedzwa kwechikwata cheropa chezvikwata:
- tsvuku (erythrocytes) - anemia ;
- white (leukocyte) - leukopenia;
- neutrophilic leukocytes - neutropenia;
- granulocytes - granulocytopenia;
- lymphocytes - lymphocytopenia;
- thrombocytes - thrombocytopenia.
Kuiswa kwezvinhu zveplasma kuvhara muropa rinogona kuderera, kufungidzira kunogona kuitika (mashoma coagulation yeropa), iyo yakazara nekubuda ropa.
Panguva imwecheteyo, pane dzimwe nguva, rutivi rwomugumisiro rweCeftriaxone ndiukoukocytosis, kuwedzera muropa remitumbi mitsvuku.
Mharaunda uye mamwe maitiro
Apo mishonga inorwisa mabhakitiriya inopindwa muvheini, kuputika kworusvingo rwaro (phlebitis) kunogona kukura, kana murwere achangotanga kunzwa kurwadziwa mumugwagwa wemudziyo. Apo mishonga inoshandiswa mukati memaoko, pane dzimwe nguva kupindira uye kunzwa kunorwadza mumutsipa.
Kune zvisiri mimwe migumisiro yeCeftriaxone yekutungamirira ndeyi:
- headache;
- Candidiasis ;
- chizoro;
- kubuda kubva mumhino;
- superinfection (kukura kwekumirisana nemishonga inorwisa mabhakitiriya, iyo inokonzera kuti utachiona humwe hukure huve humwe).
Overdose uye zvinodhaka zvakafanana
Kana zvikaitika kudarika, chirwere chechiratidzo chinogadzirwa. Hakuchina mishonga inopesana iyo inopedza simba reCeftriaxone; hemodialysis haina basa. Naizvozvo,
Ceftriaxone ine zvimwe zvinetso: inopesana nehuwandu hwevhitamini K, nokuti, semhando ipi zvayo inorwisa mabhakitiriya, inoderedza maruva emukaka, naizvozvo neyo imwe haifaniri kutora mishonga isiri-steroidal inopesana-kuvhiringidza - izvi zvinogona kuwedzera ngozi yekubuda ropa. Mushonga wacho hauna kufanana ne ethanol, saka kunwa doro panguva yekurapa kunopesana.
Aminoglycosides na Ceftriaxone, vachiita pamwe chete, kuwedzera misiro yeumwe neumwe (synergy) kurwisana nemakemikari e gram-negative.