Vose vamiririri veurongwa hwezvinodhaka-macrolides - antibacterial drugs. Maitiro avo emakemikari anobva pane macrocyclic lactone ring. Nokudaro - zita reboka. Inoshandiswa kutonga marudzi akasiyana eabhakitiriya. Uye nokuda kwekuti mari iyi inoshanda chaizvo, mushonga unoishandisa zvikuru.
Muzviitiko zvipi zvinodhaka zveboka re macrolide rinotarisirwa?
Kubudirira kukuru kwe macrolides ndechokuti ivo vari kushingaira kukuvadza hutachiona hweGr-positive. Mishonga inorwisa mabhakitiriya eboka iri inogona kukunda nyore nyore pneumococci, pyogenic streptococci, atypical mycobacteria. Pakati pezvimwe zvinhu, vanoparadza:
- legionella;
- spirochaetes;
- chlamydia;
- anaerobes (inenge zvinhu zvose kunze kwe B. fragilis);
- Listeria;
- mycoplasma;
- ureaplasmas;
- Campylobacter uye mamwe mimwe mishonga inokuvadza.
Kubva pane urongwa urwu, zviratidzo zvikuru zvekushandiswa kwekugadzirira macrolide zvakaitwa. Ipa mishonga kuna:
- streptococcal tonsilofaringitis;
- acute sinusitis ;
- pertussis;
- kuwedzera kwechirwere chisingagumi;
- Community-acquired pneumonia (kusanganisira atypical);
- diphtheria;
- periostitis;
- syphilis;
- chlamydia;
- mycobacteriosis;
- toxoplasmosis;
- exirural lymphogranulomas;
- severe acne;
- periodontitis.
Mune zvimwe zviitiko, macrolides haishandisi chete kurapwa, asiwo yekudzivirira. Saka, semuenzaniso, iyo nzira yemishonga iyi inorwisa mabhakitiriya inobatsira kudzivisa kuputika kwekukanganiswa kune avo vakaonana nevanhu vane utachiona. Mishonga inorwisa mabhakitiriya eboka iri inorayirwawo kucheneswa kwevarwere vanotakura meningococcus. Uye vanogona kuva rakanaka kudzivirira rheumatism kana endocarditis.
Mazita emishonga-antibiotics boka re macrolides
Zvichienderana nehuwandu hwekombemu maatomu ari pamhete ye lactone, mishonga yacho yakakamurwa kuva mapoka e14-, 15- kana 16-nhengo. Mukuwedzera kune chokwadi chokuti mishonga iyi inorwisa mabhakitiriya inoparadza zvirwere, inobatsirawo kusimbisa hutachiona uye inokwanisa kubvisa kwete kunyanya kufambira mberi nekuputira maitiro.
Mishonga inorwisa mabhakitiriya-macrolides inosanganisira madhiragi akadaro:
- Erythromycin inofanira kutorwa kusati kwadyiwa. Kana zvisina kudaro, kubhadhakwa kwayo kuchave kwakanyanya kuderedzwa. Pasinei nekuti iyo yakasimba yemishonga inorwisa mabhakitiriya, ine chido chakanyanya chokunwa iyo inobvumirwa kunyange panguva yekudzivirira uye lactation.
- Spiramycin inoshanda kunyange kupikisa mabhakitiriya aya anowirirana nema macrolides ane gumi nemana nemashanu. Iyo yakaiswa mumasukisi yakakwirira chaizvo.
- Iyo macrolide drug, inonzi Clarithromycin , inorwisana neHelicobacter uye atypical mycobacteria.
- Roxithromycin therapy inonyatsorambidzwa nevarwere.
- Azithromycin yakasimba zvokuti inofanira kutorwa kamwe chete pazuva.
- Kuzivikanwa kwaJosamycin kunotsanangurwa nebasa rayo rinopesana nehuwandu hwemhando dzakasiyana dze strepto- uye staphylococci.
Zvinenge zvese macrolides kubva mune urongwa hwezvinodhaka zvinogona kupiwa mazita ebronchitis. Mukuwedzera kune izvi, kurwisa mabhakitiriya inogona kushandiswa:
- Dynabac;
- Ilozon;
- Azidrop;
- Azivok;
- Zimbactur;
- Wilprafen;
- Binocular;
- Benzamycin;
- Azicid;
- Klabaks;
- Azitral;
- Esparoxy;
- Brilid;
- Rovamycin;
- Crixan;
- Macropean;
- Clacid;
- Rulicin;
- Sumamed ;
- Hemomycin;
- Zitnob;
- Kispar;
- Sumatrolide solute;
- Clerimedes;
- Elrox;
- Coater;
- Zitrocin;
- Eryfluid;
- Ecositrin;
- Fromromide;
- Arvitsin;
- AsitRus;
- Azimycin.