Kazhinji vanhu vanozivikanwa nehutachiona hunopesana nemishonga inofungidzirwa seboka rekudzivirira mafungiro uye kushandiswa kwevanhu. Iyo inobudiswa kubva muropa revadzidzisi vane hutano vakagadziriswa zviongorori zvekliniki chaiye uye kuongororwa kwe laboratori uye havana uchapupu hwehutachiona hunotakura ropa (kunyanya, hutachiona hweHIV, hepatitis C uye B).
Chimwe chikamu chikuru chechirwere ichi chikamu chechirwere chemuviri chine ropa reprotein, iro rinowanzoita immunoglobulin G uye rine immunoglobulin M uye immunoglobulin A mune zviduku zvishoma. Kugadzirira kunonyatsocheneswa, kuiswa mukati uye hutachiona husina kushandiswa panguva yekugadzira. Kazhinji manyowa immunoglobulin haana mazvigadziro uye antibiotics, sechigadzirisa zvine glycine.
Kubudiswa kusununguka uye nzira yekushandisa shanduko yevanhu immunoglobulin
Mishonga inogona kubudiswa muchimiro chemhinduro, yakaiswa mumaboules, kana se lyophilizate yekugadzirisa mhinduro, yakaiswa mumabhodhoro. Mune chimiro chemvura yakasvibiswa kana isina kuchena, yakajeka. Irophilisate yemunhu anowanzozivikanwa nejinga remunoglobulin inonzi white porous hygroscopic mass. Munhu immunoglobulin inoshandiswa nokuda kwemuviri (injections) uye intravenous (dropper) administration.
Zvigadzirwa zvevanhu vanowanzozivikanwa neunofunoglobulin
Mushonga wacho une zvinhu zve immunoglobulin G, iyo inowanikwa mune vanhu vane utano. Painoiswa, zvinotevera zvinowanikwa:
- kugadzirisa kwekushayikwa kweGG, iyo inobatsira kuderedza njodzi yekuvandudza zvirwere zvakasiyana-siyana;
- kudzoka kwechikamu chechidiki cheGG kusvika kune zvakanakira tsika;
- kuwedzera kusina kunyatsopikisa kwemuviri womunhu;
- kudzvinyirira uye kutapudza kwebhakitiriya yakasiyana-siyana, mavairusi nezvimwe zvinotapukira.
Zviratidzo zvekushandiswa kwemazuva ose ekuzivikanwa kwevanhu: immunoglobulin:
- congenital antibody inoshaya syndrome;
- general variable immunodeficiency;
- iatrogenic immunodeficiency;
- chronic lymphocytic leukemia;
- myeloma;
- thrombocytopenic purpura yekuzvidzivirira kwezvirwere nehuwandu hwekuwedzerwa ropa;
- Kawasaki's disease;
- bone marrow transplantation;
- zvirwere zvakakomba zvakabva kumarudzi akasiyana;
- bacterial meningitis;
- Guillain-Barre syndrome;
- kunyorera kupisa kwema polyneuropathy mumamiriro asingagumi;
- hemolytic anemia;
- thrombocytopenia yemuviri wemuviri;
- autoimmune neutropenia;
- chikamu chikamu chekundu aplasia ye hematopoiesis;
- myasthenia gravis ;
- kazhinji kupererwa kwepasipo;
- hepatitis A;
- masero;
- poliomyelitis;
- furuwenza;
- unopfugama kukomba;
- meningococcal infections, nezvimwewo.
Zvimwe zvinokonzera uye zvinopesana nezviitiko zvevanhu vanowanzozivikanwa
Migumisiro yekutora kutaridzika kwevanhu immunoglobulin:
- kuwedzera kwekushisa kwemuviri;
- kurwadziwa mumusoro;
- nausea;
- tachycardia;
- ruvara rwekutsvaga panzvimbo yejojo;
- kutuka, nezvimwewo.
Kupindirana kwekuiswa kwechimiro chevanhu vanowanzozivikanwa: immunoglobulin:
- hypersensitivity kumunhu immunoglobulin, michina yeropa;
- kuvapo kwezvirwere kune IgA.
Nehanya, mushonga unoshandiswa apo:
- pamuviri, nekuyamwisa;
- chirwere cheshuga mellitus;
- kuwedzera kwezvinhu zvinokonzera matanho;
- renal failure;
- nephrite;
- migraines;
- decompensed chronic heart failure;
- zvirwere zvezvirwere zveropa;
- collagenosis, nezvimwewo.
Uyewo, paunenge uchishandisa mushonga uyu, unofungidzirwa kuti hutungamiri hwahwo hunokanganisa kukanganisa kwezvirwere zvirwere zvinopesana nezvirwere zvakadai se rubella, masero, makumbo uye huku.