Ropa revanhu rinosanganisira marudzi akawanda emapurotini, ayo anofanira kunge ari mune imwe chiyero chekuita mabasa avo. Chimwe chazvo ndeye fibrinogen, iyo yakawanda inotsanangurwa muhutano hwehutano hwekuvhara ropa. Kana zvakaguma zve fibrinogen zvakakwirira kudarika zvinowanzoitika, izvi zvinorevei, zvakakosha kuziva.
Fibrinogen - chii ichocho?
Chaizvoizvo, chii chinonzi fibrinogen, varwere vakawanda vanofarira apo vanoona migumisiro ye coagulogram - chidzidzo chebhishopi cheropa rinouraya, iro rinobvumira munhu kuongorora kubatana kwayo. Kazhinji, kuongororwa uku kunorayirwa vasati vasvika pakusangana kwakasiyana-siyana, pakuberekwa, nekufungidzirwa kwehumwe hutachiona (chiropa, mwoyo, vascular system, nezvimwewo).
Puroteni fibrinogen inobudiswa neropa rechiropa uye, kupinda muropa, inopararira ikoko muhurumende isingagadziriswi. Icho chimwe chezvikonzero zvekuvhara ropa. Pamusana pemaitiro akaoma ekugadzirisa mukutarisana nemigumisiro inoshungurudza, mudziyo wakagadzikana wakavharwa nejira rinodzivirira kubuda ropa. Nheyo yekuumbwa kwevhatta (thrombus) haina kusvibiswa fibrin protein, inowanikwa nekuparadzanisa fibrinogen ne thrombin enzyme.
Mukuwedzera kubatanidzwa mukugadzirwa kwe-thrombus, fibrinogen inokurudzira kuumbwa kwevhisi vesicles uye kushamwaridzana kwemasero, uye zvinoratidzawo kupisa kwemapurogiramu. Kuderedza muhupamhi hwayo kunokonzera kuora kwekuvhara ropa, kunokonzera kubuda ropa kwenguva refu, uye yakakwirira fibrinogen inotungamirira kusagadzikana kwekugadzirwa kwetrombi kunyange pasina kukanganisa kumadziro edzimba.
Kutsunga kwe fibrinogen
Mune ma laboratori, fibrinogen muropa inoshandiswa nemaitiro emagetsi. Kuti urege kudzikanganisa, zvinotevera zvinofanirwa kuonekwa zvisati zvaitika:
- kutora zuva rekudzidza kana pane zviratidzo zvezvirwere zvecatarrha;
- kubviswa kwezvokudya, kunwa kofi, tei, zvinwiwa zvinodhaka 12 maawa asati asvika;
- kubviswa kwehutungamiri hwemafarisi ehutachiona anokonzera ropa coagulation, mazuva mashomanana usati wadzidza (sekurairwa nachiremba);
- kudzivirira kushanda muviri, kushungurudzika mupfungwa kusati kwaongorora;
- kuramba kusvuta bhana maawa mashoma;
- Kutora girazi remvura yakachena kwechitanhatu cheawa imwe isati yatora ropa.
Fibrinogen muropa - inowanzova vakadzi
Fibrinogen muropa, iyo inowanzoenderana nezera remunhu, inofanira kuchengetwa mumwero we 2-4 g / l muvakadzi vakuru vane utano, pamwe chete nevarume. Muvana, izvi zvinodhura zvishoma. Kana, maererano nemigumisiro yekutsvaga kwe fibrinogen, chimiro chevakadzi chinoonekwa, izvi zvinoreva kuti puroteni iyi inogadzirwa mune zvakakwana, mikana yekuvhara ropa iro haiputsi.
Fibrinogen mukudzivirira inowanzoitika
Fibrinogen, iyo inowanzo isiri yakasimba kune vanhu vane hutano, inoshandura iyo yakarongeka inowanikwa apo mukadzi anotakura mwana. Izvi zvinokonzerwa nekuumbwa mumutumbi waamai weutachiona hutsva, hunosanganisira placenta. Pakutanga, huwandu hweprotini iyi hahuwandise, asi mumagumo ekupedzisira, fibrinogen mumadzimai ane pamuviri anosvika pakakwirira, iyo inofanirwa kudzivirira kurasikirwa kukuru kweropa panguva yekuberekwa. Maitiro anotevera:
- Ini ndinotarisa - 2,5-5 g / l;
- II trimester - 2.5-5.1 g / l;
- III trimester - 3.7-6.1 g / l.
Fibrinogen yakawedzera - zvinorevei?
Apo kuongorora kunoratidza kuti fibrinogen yakakwirira kudarika yakasarudzwa, zvinoreva kuti murwere ane huwandu hwekuwedzera kwehutachidzo - kuwedzerwa kwechikwata chevascular pamwe nekudziviswa kweropa reimwe nhengo kana chikamu chemuviri. Iyi mamiriro ezvinhu anotyisidzira kukura kwehosha yeconary heart, myocardial infarction, stroke, i.e. yakaipisisa pathologies.
Dzimwe nguva fibrinogen inogona kuwedzerwa zvishoma kana kwechinguva nezvinhu zvinotevera:
- kumwedzi;
- yekare operative intervention;
- ikozvino kupisa, zvimwe zvinetso;
- low temperatures ambient temperatures.
Mukuwedzera, fibrinogen yakareba kupfuura yakasarudzwa muvakadzi vanotora estrogen-ine mishonga. Zvinonyanya kuoma kupfuura mamiriro ezvinhu ekureba kwenguva refu fibrinogen yakakwirira zvakanyanya kudarika yakasarudzwa, uye izvi zvinoreva kuti kupisa kana zvimwe zvirwere zvinokonzera muviri zvinowanikwa mumuviri. Zvichida zvinokonzera ndezvi:
- zvirwere zvakanyanya zvechirwere uye zvinopararira zvekunzvimbo dzakasiyana-siyana (tuberculosis, pyelonephritis, pancreatitis, etc.);
- nyangadzi dzisina kunaka;
- mhando dzakawanda dze hypothyroidism ;
- kufa kukuru kwemasukisi (pancreatic necrosis, kupumbuka kwemapapu , gumbo, nezvimwewo);
- zvirwere zve autoimmune muchikamu chinoshanda (rheumatoid arthritis);
- kukanganisa kumativi ezvipembenene (chirwere cheshuga chirwere chekushaya chirwere cheshuga, kusagadzikana kwemawere kusingaperi, varicose veins, etc.);
- thrombohemorrhagic syndrome (kutanga danho);
- amyloid dystrophy, nezvimwewo.
Fibrinogen yakakwirira mukudzivirira
Kana iyo fibrinogen panguva yekuzvitakura inopfuura kudarika kwepamusoro, zvikonzero zvinogona kunge zvakafanana. Iyi mamiriro ezvinhu haangovhundusisi chete hutano uye hupenyu hwemamazuva anouya, asi hunoisawo nguva yekudzivirira. Migumisiro inogona kuva seyizvi:
- kuparadzaniswa kwepasipo;
- placental abruption;
- thrombosis yembilical cord;
- kusununguka nguva isati yasvika, nezvimwewo. fibrinogen pamusoro pezvinowanzoita kuti izvi zvinoreva fibrinogen pamusoro pezvakanaka aaa zvinorevei
Fibrinogen yakawedzerwa - chii chaungaita?
Mumamiriro ezvinhu apo kuwedzerwa kwe fibrinogen kunoonekwa, zvinova zvakafanira kuitisa mimwe miti miviri yekuona kuti chii chinokonzera. Kungoti mushure mekunge izvi zvinogona kutsanangurwa nechirongwa chokurapa, chinangwa chekugadzirisa chirwere chepfungwa. Nokuda kwekuderera kunononoka muhuwandu hwepuroteni iyi, mishonga inobva muboka re antiplatelet agents , fibrinolytics, anticoagulants inogona kurongerwa, kudya pamwe nekuderedza cholesterol kudya, zuva rega rekuita muviri, kutonga kwakakwana kwekunwa kunorudzirwa.