Aminoglycosides inosanganisira boka remishonga inorwisa mabhakitiriya inoratidzirwa nechimiro chakafanana, chirevo chekuita uye nehuwandu hwehutsinye. Aminoglycoside magadzirira ane antimicrobial yakajeka uye inopesana neBram-positive uye Gram-negative bacteria.
Urongwa hwemaminoglycosides
Zvichienderana nemunda wekushandiswa uye nguva yakawanda yekukura kwekuramba, zvizvarwa zvina zvemishonga inopiwa. Ngationgororei maitiro anokosha uye tichaita kuti mazita emazita ekugadzirira-aminoglycosides.
Chizvarwa Chekutanga Mishonga
Izvi ndezvi:
- Neomycin;
- Streptocin;
- Monomycin;
- Kanazin.
Iyo inoshandiswa mukurapa kurwisa zvirwere zvechirwere chetachiona uye mamwe mabhakitiriya anypical. Kupikisa staphylococci uye mabhakitiriya akawanda-gramu, zvinodhaka hazvina simba. Iye zvino ivo vanenge vasingashandisi.
Aminoglycosides wechipiri chizvarwa
Mumiriri weboka rechipiri remishonga inorwisa mabhakitiriya-aminoglycosides iGentamicin, iyo inoshanda zvikuru kupfuura boka rekare remishonga.
Chizvarwa chechitatu che aminoglycosides
Izvo zvinokonzerwa nezera rechitatu zvakafanana neGentamycin, zvisinei kuti zvinoshanda zvakanyanya kurwisa enterobacter, klebiciella uye Pseudomonas aeruginosa . Iri boka rinosanganisira:
- Sisomycin;
- Tobramycin;
- Amicacin.
Chizvarwa chechina
Iri boka rinobatanidza mishonga inorwisa mabhakitiriya Izepamycin, iyo inowedzera inokwanisa kukwikwidza necardia, cytobacter, aeromonas.
Zvimwe zvikamu zveaminoglycosides
Penguva yekurapa nemishonga iyi, murwere angasangana nezviitiko zvisingadikanwi. Iko kutsvaga kwekushandisa kwezvinodhaka ndiko kutyisa. Zvinoratidzika pane zviratidzo zvinotevera:
- Ototoxicity, iyo inokonzera kudonha mumusana wekunzwa, kutaridzika kworuzha munzeve, kunzwa kwekunaka.
- Nephrotoxic effect, zviratidzo zvaro zvine nyota, zvinoshandiswa muhuwandu hwemuti, kuderedzwa kwezvinonzi filmerular filtration.
- Kuwedzerwa kwekubatanidzwa kwekufamba uye chizivo, izvo zvinonyanya kufanana nevanhu vakwegura.
- Pane chikamu chehurongwa hwemitsipa, kupera mumuromo, kupera simba, kushaya simba, kuora musoro, kutinhira kunokonzera, kurara kunoonekwa.
- Kuonekwa kwezviratidzo zvehutachiona hunovharidzirwa, kuratidzirwa pakuwedzera kwekufema kunoshanda kusvika pakuora mitezo kunokonzerwa nekufema kwemisumbu, kunowedzera dambudziko nekufananidza kwehutano hwemishonga inorwisa mabhakitiriya-aminoglycosides nemisumbu inononoka uye anesthetics, uyewo nekuwedzerwa ropa rakawanda.
Zviratidzo zvehutachiona hazviitiki.