Iko kukanganisa kukuru kweavo vose vanobudirira diuretics (diuretics) ndeyekuwedzerwa kwe potassium uye magnesium kubva mumuviri pamwe chete nemafuta akawanda. Veroshpiron ndeyeboka rezvinodhaka izvo zvisingabatanidzi kuwanda kwezvinhu izvi zvemakemikari. Mune zvimwe zviitiko, iyo inobatsira nekukurumidza kudzorera iyo kunzvimbo yakagamuchirwa.
Veroshpiron - kuumbwa
Izvo zvinoshandiswa zvinoshandiswa pamishonga inotsanangurwa ndeye spironolactone. Ichi chinhu chinonzi mineralocorticoid hormone inopikisa, iyo inobudiswa ne-adrenal glands uye inosimudzira kuunganidza kwehutu uye sodium inyu mumasukisi (aldosterone). Mushonga weVeroshpiron mumarudzi akasiyana-siyana ekubudiswa ane zvingabatsiri zvikamu:
- colloidal silicon dioxide;
- talc;
- magnesium stearate;
- lactose monohydrate;
- corn starch;
- sodium lauryl sulfate;
- titanium dioxide;
- gelatin;
- dye.
Veroshpiron chii?
Icho chikuru chinokonzerwa ne spironolactone chinonzi diuretic. Izvi zvinokonzera kukanganisa kwakanyanya, uko kunobatsira Veroshpiron - zvinowanzoitika zvechimiro chakasiyana uye zvakabva. Mishonga inonzi yakataurwa inoonekwa senzira yakachengeteka yekubvisa kuwedzera kwemvura, nokuti haipindirani ne electrolyte nemakero emunyu mumuviri.
Veroshpiron - kuverenga:
- kusingaperi mwoyo kukundikana ne edematous syndrome;
- Inokosha hypertension (spironolactone inowanikwa muchirongwa chemaitiro akaoma);
- yechipiri hyperaldosteronism kumucheto wechiropa che cirrhosis , ascites, nephrotic neson uye zvimwe zvirwere;
- paroxysmal myoplegia;
- hypomagnesemia;
- Connes syndrome;
- hypokalemia.
Kune imwe nzvimbo iyo Veroshpiron inoshandiswa - zviratidzo zvekushandisa zvinosanganisira hyperprolactinemia. Spironolactone ine nzvimbo yekuderedza kuwedzera kwekuwedzera kwehomhoni yehomoni. Iyo inodzivisa kuwedzera kwekugadzira kweprolactin, saka inowanzorongedzerwa nevadzidzisi vegynecologists-endocrinologists nematambudziko anokonzerwa nehutano hwekuberekwa kwevakadzi, kusanganisira cystic, fibrous uye yakazara mastopathy.
Nzira yekutora Veroshpiron?
Zvikamu uye nguva yehutachiona ne spironolactone inobva kune chirwere chinorwara uye zvimwe zvinosanganiswa nezvirwere. Mushonga weVeroshpiron mune mamwe mamiriro ezvinhu unotarisirwa zvakafanana ne thiazide (loop) diuretics, iyo inopa zvakanyanya kuzivikanwa uye nokukurumidza. Zvikamu uye nguva yehutano inongororwa chete neyanyanzvi. Zviri nengozi kunwa Veroshpiron iwe pachako - iyo dhesi yakasarudzwa zvisina kururama inogona kutungamirira kumigumisiro yakaipa. Chimwe chinetso chinowanzoitika chemaitirwo emishonga ndekukuvhiringidza kwakanyanya kwepfungwa.
Nzira yekutora Veroshpiron nekudzimba?
Munyaya yekusagadzikana kwemoyo mwoyo spironolactone inokurudzirwa kushandiswa kwemazuva mashanu ezana (marefu - 200) mg, yakakamurwa ne 2-3 nguva. Veroshpiron mukuputira pakatarisana nehutachiona hwehuwandu hwehutano hwakakosha hunorayirwa muwandu hwe 50-100 mg kamwe kamwe pazuva. Zvishoma nezvishoma (masvondo maviri ose) muyero unowedzera kusvikira unosvika 200 mg. Chikoro chetachiona chemahara chinenge mazuva 14.
Kana kukanganiswa kuchiitika nekuda kwechirhosis chechiropa, spironolactone inoshandiswa maererano neyero ye potassium uye ionic ion mumugini. Apo chiyero ichi chiri kupfuura 1, chikamu chezuva nezuva cheVeroshpiron chiri kusvika ku100 mg. Pamwero wepasi pe1, spironolactone inokurudzirwa muhuwandu hwe200-400 mg. Nhamba yega yekugadzirisa yakasarudzwa.
Kurapa uye kusiyana kwehutano hwe hyperaldosteronism uye nephrotic syndrome, chirwere chimwe chete chinobva pa100 kusvika 400 mg. Chiremba wake anoverenga pane imwe nhamba ye data pamusoro pemafungiro echirwere uye kuwedzera kwe potassium muropa. Nhamba yezuva nezuva inotorwa kune 1 kana 2-4 dzimwe nguva, zvichienderana nechinangwa cherapi, chirwere chedema uye kushivirira kwemishonga.
Varwere vakawanda havafariri nguva yokunwa Veroshpiron - vasati vadya kana mushure mekunge, asi kudya kunonyanya kuchinja kubudirira kwemishonga. Zviratidzo zvehupenyu uye kugadzika kwe spironolactone kuwedzera kana inopinda mumuviri pamwe chete nezvokudya. Nyanzvi dzinokurudzira kushandisa mishonga zvakananga mushure mekudya uye uchiinwa ne 0.5 magirasi emvura.
Nzira yekutora Veroshpiron yekureruka kwekukura?
Iyo yakatsanangurwa mishonga ndeyemishonga yakakomba iyo inobvisa kukwezva kwakanyanya uye kuparara. Kushandisa Veroshpiron kuti uremekedze hazvibviri, haisi kungofanana chete, asiwo kune ngozi. Spironolactone haina kuchinja huwandu hwemafuta aripo, asi zvinongobvisa kunyanya kudarika kubva mumuviri. Kana ukashandisa senzira yekuderedza uremu kana "kuomesa", inogona kukanganisa zvirwere zvekuvhenekera uye itsvo.
Veroshpiron panguva yekuzvitakura
Pakuunza spironolactone zvinopesana. Ichi chinhu, chine bhiwavailability yakakwirira, chinopinda mumugwagwa wepakati uye chinopinda muropa remwana. Pakarepo mushure mokuberekwa, zvakare, iwe haugoni kunwa Veroshpiron - zviratidzo zvekushandiswa kusachengetedza uye lactation. Izvo zvinoshandiswa zvinoshandiswa zvechirwere zvinoshandiswa mune zvose biofluids uye zvinosvika mumatokari anenge 100%, kusanganisira mukaka wemvere. Veroshpiron mune gynecology inoshandiswa chete mukurapa hyperprolactinaemia uye zvirwere zvakabatana. Urongwa uhwu hunosanganisira kusaziva uye endocrine kusununguka.
Veroshpiron anotora nguva yakareba sei?
Nguva yenguva yekurapa inoratidzwa nachiremba mushure mekunyatsoongorora. Usatora nguva refu kunwa Veroshpiron - kushandiswa kwe diuretic kwemavhiki anopfuura mana kunogona kukonzera kukanganisa mu electrolyte, munyu nemvura metabolism. Kakawanda kacho kunetseka kwehutano hwakadaro kwenguva refu urate diathesis kana hyperuricuria. Diuretic Veroshpiron yakakurudzirwa kushandisa kwemazuva 5-15. Pamberi pezviratidzo, mudiki wekugadzirisa chirwere chechirwere chinosarudzwa.
Veroshpiron - madhara
Zvinhu zvisingaiti ne spironolactone hazvishamisi, asi zvinosanganisira yakawanda mazita ehutano hwemamiriro ezvinhu. Veroshpiron - nemigumisiro yekushanda:
- kurutsa;
- diarrhea;
- nausea;
- gastritis;
- kusuruvara muzvikamu zvepepa remimba;
- kuzvidzora;
- intestinal colic;
- kurwadziwa mu epigastrium;
- kukanganisa kwechiropa kunoshanda;
- chizoro;
- ataxia;
- kugona;
- kukanganisa;
- kuvhiringidzika kwekuziva;
- lethargy;
- headaches;
- thrombocytopenia;
- agranulocytosis;
- megaloblastosis;
- hypercreatininaemia;
- hyperuricemia;
- alkalosis;
- hyponatremia;
- metabolic acidosis;
- hyperkalemia;
- gwapa izwi;
- gynecomastia;
- dysmenorrhea;
- kukanganisa kwekutenderera;
- hirsutism;
- metrorrhagia;
- amenorrhea;
- kunhuwa kweganda;
- urticaria;
- fever;
- hypertrichosis;
- kidney failure;
- alopecia;
- kunetseka;
- misuli spasms.
Veroshpiron - zvinopesana
Kune zvirwere umo spironolactone yakarambidzwa zvachose, uye mamiriro ezvinhu iyo inogona kushandiswa nekuchenjerera. Muchiitiko chekutanga, iwe unofanira kutora Veroshpiron - chiito chechirwere chinongokuvadza chete. Kutaura zvinopesana nezvinyorwa zvekushandisa:
- hyperkalemia;
- Chirwere cheAdisonison ;
- renal insufficient mumugariro wakaoma;
- hyponatremia;
- lactose kuvolerance;
- anuria;
- chirwere chekushaya glucose kana galactose;
- pamuviri;
- kukwana kwe lactase;
- anokwana makore matatu;
- lactation;
- hypersensitivity kune chero chinhu chinobatanidzwa mumushonga.
Mune mamwe mamiriro ezvinhu, ndiye chiremba chete anosarudza kuti zvakakodzera sei kuisa Veroshpiron - zviratidzo zvekushandisa zvinogona kusanganisira zvirwere zvinotevera umo kushandiswa kwakanyatsogadziriswa kwe diuretic kunodiwa:
- metabolic acidosis;
- hypercalcemia;
- chirwere cheshuga mellitus;
- Vadzivisa;
- kusangana kwemwedzi;
- hepatic insufficiency;
- diabetes nephropathy ;
- kusagadzikana kusina kuchena kwema mammary glands;
- chirwere chechiropa;
- kukwegura.
Veroshpiron - zvakafanana zvekugadzirira
Dzorera diuretic nemishonga ine zvakafanana. Kana Veroshpiron ine zviratidzo zvekushandiswa, zvakanyatsobatana nemashoko ekufananidzira, zvakakosha kuwedzera kuwedzera zvivako zvemutambo. Inofanira kuvhiringidza leaching ye magnesium nemasitinium salt, asi uchichengetedza sero re electrolyte mumusasa. Veroshpiron - zvakafanana nezviratidzo zvakafanana zvekushandiswa:
- Spironolactone (zvakananga);
- Epletor;
- Renial;
- Eridanus;
- Dekriz;
- Epplepres;
- Inspra;
- Espiro.