Zvose zvinokonzerwa nemararamiro ari mumuviri womunhu zvinodzorwa nemahomoni. Izvi zvimakemikari zvinokanganisa kwete chete zvisikwa, asiwo maonero emanzwiro, kunyanya kuvakadzi. Kunyangwe kudengenyeka kwepakati pekugadzirisa kwechigodhi kubva kuchimiro kunogona kuwedzera kuwedzera hupenyu hwehutano uye kunokonzera zvinetso zvakakomba.
Iro hormone yehutori-inokurudzira - chii ichi muvakadzi?
Izvo zvinorondedzerwa zvinhu zvinogadzirwa mune anterior pituitary gland, kuvharwa kwayo kunotungamirirwa ne-central central nervous system (nokuda kwechikamu chikuru). Iyo hormone TSH kana thyrotropin inonzi glycoprotein ine zvinotevera zvinowanikwa pamuviri wevakadzi:
- kudzora kwekugadzirwa kweT3 (triiodothyronine) uye T4 ( thyroxine );
- mutemo wekuenda kumwedzi, mabasa ekuberekwa uye mumatumbo motility;
- kuve nechokwadi simba remuviri;
- kupinda muhutano hwevhitamini A, phospholipids, nucleic acids uye mapuroteni;
- kuenzanisa kwebasa rezvikamu zvekuona, kunzwa, mwoyo uye zvirwere zvekutya;
- kunatsiridza iodini kufanana nekurohwa kwetachiona masero;
- kugadzikana kwekushushikana kwepfungwa kunokonzera kushungurudzika.
Kazhinji, pane mashoko asina kunaka T3, T4 uye TTG. Nekuwedzera kana kupinza kwakapinza mumusana we triiodothyronine uye thyroxine mu plasma yeropa, chirwere chetachiona chinoratidza chimiro chepituitary ye kusaenzana. Somugumisiro, simba rekugadzirwa kwe thyrotropin rinosiyana, kuitira kuti kunyatsorongororwa kwakakosha kunoda kuziva nhamba yezvipembenene zvehupenyu muhutano.
Kuongorora mahomoni - TTG
Icho chemikemikari iri mubvunzo inoratidzirwa nekuchinja kwezuva nezuva mumatongerwo emitemo. Iyo yakawanda yepamusoro yeplasma inoonekwa pakati pemaminetsi maviri nemaawa mana eusiku. Pakazosvika 6-8 am, thyrotropin inotanga kuderera, kusvika kune imwe nguva manheru, saka ropa paTTG zviri nani kutora mangwanani. Kana iwe ukaramba wakamuka usiku, kubudiswa kwehomoni kunopera simba.
Kugadzirira kwekuendeswa kweropa reTTG
Kuti uone zvakananga kuwanda kwee thyrotropin, zvose zvinokonzera zvinogona kukanganisa migumisiro yekudzidza zvinofanira kubviswa. Nyanzvi dzinokurudzira mangwanani kuti titore TTG - kuongorora ropa mumaawa ekutanga kunobatsira kutsanangura kukosha kwechokwadi, pedyo nepamusoro. Zvakakosha kuva nehope dzakanaka usati wamboenda kub laboratory, zvisinei kana kuvimbika kwechidzidzo ichi kuderera.
Usati watora kuongororwa ropa kweTTG, unoda:
- Usadya kwemaawa masere.
- Rega kusvuta pazuva rokudzidza.
- Pausiku wekushanyira kub laboratory, sarudza zvokudya izvo zviri nyore kudya, uye usadya zvakanaka.
- Dzivisa muviri uye kuora mwoyo.
- Usanwa doro kwemazuva mashanu usati waongorora.
Thyrotropic hormone inowanzova vakadzi
Mune ma laboratori akasiyana-siyana, hutsika hwehutauriri hunotsanangurwa hunopesana zvichienderana nekunzwisisika kwemidziyo, saka ndiyo tsika yekuratidza zvinoratidzwa zviratidzo. TTG - inowanzoonekwa nevakadzi nezera (mIU / l):
- 14-25 makore - 0,6-4,5;
- 26-50 wemakore - 0.4-4.0;
- mushure memakore 51 - kusvika kusvika 4,5.
Kunyatsoteerera thyrotropin kunofanira kupiwa kuvadzimai, kusvika kune makore makumi mana. Iyi nguva inotanga kusvika kumwedzi, saka kukanganisa kwehomoni uye zvinetso zvakabatana zvinogona kunge. Mushure mokunge apera, zvinokoshawo kugara uchitarisa hutachiwana hweTSH - chimiro chechiratidzo ichi hachifaniri kudarika mamiro e 0.4-4.5 mIU / l. Kuwedzera kana kuderera mu thyrotropin kune hutachiona hwezvirwere zvehutano uye zvirongwa zvehupenyu izvo zvinodzora.
TTG inokurudzirwa kana kuwedzera - zvinorevei kune vakadzi?
Kakawanda kamwe kemukato kuwedzera mumusanganiswa wemakemikari inowanikwa inoonekwa navanachiremba sechinhu chakasiyana chechimiro. Iyo hormone yehutachiona-inokurudzira inosimudzwa mumiganhu inogamuchirwa maererano nemamiriro ezvinhu akadaro:
- kusagona kwehope;
- kuwandisa muviri;
- kushungurudzika kana kushungurudzika mupfungwa;
- kuputsa kwemitemo yekugadzirira kuongorora;
- kushandisa zvakanyanya iodine.
TTG yakakwirira - zvinokonzera
Kana thyrotropin mu plasma yeropa yakareba kwazvo kupfuura yakasarudzika, unofanirwa kuonana ne-endocrinologist. Chenguva chete nyanzvi ichakwanisa kuziva kuti nei hormone yehutori-inokurudzira yakakwirira - zvinorevei izvi, hazvigoni kuongororwa pamusana pemigumisiro yekuongorora kumwe uye kuongorora kwepanyama. Kuti uone kuti chii chinokonzera dambudziko racho, iwe uchafanirwa kuongorora zvidzidzo uye uone kuisa kweT3 neT4.
Pane hutano hutano hunoita hutachiona-hunokonzera hormone - chimiro chinowedzerwa mumatambudziko anotevera:
- kuputika kwetachiona gland;
- hypothyroidism ;
- kutyisa neutungamiri makemikari;
- primary decompensated renal failure;
- chirwere chakakomba mupfungwa;
- kudzivirirwa kwemasukisi kune utachiona hwehomori;
- matumbo;
- gestosis ;
- kushungurudza kwepakati yenheyo system;
- Hashimoto's thyroiditis nevamwe.
TTG yakakwirira - kurapwa
Kurapa kwedambudziko iri kunobva pamashoko asina kunaka, anosanganisira utachiona-hunokurudzira hormone uye thyroxine. Kuita kuti mamiriro acho ezvinhu adzoke kuwedzerwa kuwedzera kwema plasma yeT4. Apo TSH yakakwiridzirwa, mupurologistist anorongedza kushandisa mishonga ne thyroxine zvakagadzirwa. Nhamba, nguva yakawanda yekushandiswa uye nguva yehutano kuvakadzi inotarirwa mumwe nomumwe. Kugadzirira zvinobudirira:
- Bagotiroks;
- Zviitiko;
- Euterox;
- Thyreotome;
- L-thyroxine uye zvakafanana.
Hemoni inogadzirisa hutoni inoderedzwa - zvinorevei?
Sezvakaita munyaya yekuwedzera, kuderera kuduku kwehuwandu hweTSH hachiri chiratidzo chekukuvadza. Madzimai, dambudziko iri dzimwe nguva rinoitika nekuchinja kwekuenda kumwedzi. Low TSH sechinhu chakasiyana-siyana chechimiro chinoonekwa maererano nemamiriro ezvimwe zvinhu:
- nzara kana kutevedza kudya kwakasimba kwekurasikirwa nekurema;
- kushandisa zvinodhaka zvinoderedza utachiona hweganda;
- kushungurudzika muusiku wekuongorora;
- kushandiswa kwakashata kwemadonal madawa.
TTG yakaderera - zvikonzero
Kana uwandu hwezvinhu zvakasikwa zvakanyanya kudarika zvinowanikwa, zvinokosha kushanyira chiremba pakarepo. Zvirwere uye zvirwere zvinokonzerwa nehutachiona-zvinosimudzira hormone inoderedzwa:
- matumbo ehutachiona;
- encephalitis;
- iyo Itenko-Cushing syndrome;
- meningitis;
- Grevs disease;
- Shihan syndrome;
- neoplasms munharaunda yepituitary;
- thyrotoxicosis;
- Plummer's syndrome;
- kuora mwoyo nevamwe.
TTG inoderedzwa - kurapwa
Kuchengetedza zvinyorwa zve thyrotropin mu plasma yeropa zvinodiwa kuti utsungirire chirwere chepachivi uye zvakafanana nekushanda mahomoni anogadzirwa. Nhamba yeTSH inogona kuwedzerwa nemishonga inoshandiswa, iyo inongororwa chete neyemagokorinologist mumwechete:
- Parasosin;
- Amiodarone;
- Methimazole;
- The ipodeyt;
- Erythrosine uye zvakafanana.
TTG mukudzivirira
Mumazuva anotevera vanaamai, chirongwa che endocrine chinoshanda zvakasiyana, nokuti mahomoni emwana haasati agadzirwa. Kubvira panguva yekutenda uye nhamba yemambrus, kutungidzirwa kweTSH - chimiro muvakadzi vanogadzirira kuonekwa kwecheche (mIU / l) inobvawo:
- 1 trimester - kusvika ku 0.4;
- 2 trimester - 0,3-2,8;
- 3 trimester - kusvika ku3,5.
Pakarepo mushure mekubata pamuviri, imwe inoderera mu thyrotropin unhu. Izvi zvinokonzerwa nekuwedzerwa kweropa kuhutano hwetroroid, ndicho chikonzero T3 neT4 yakagadzirwa inoitwa. Mukurwisana kwemashure emashoko asina kururama, kuwedzerwa mumatambudziko avo kunotungamirira kudzvinyirira kwekugadzirwa kweHormone yakatsanangurwa. Kana paine huwandu hwemucheche mubereki, chiratidzo ichi chinogona kuenzana ne zero, nyika ino inofungidzirwa sechimiro chechimiro.
Kana TTG ichikwiridzirwa pamuviri, zvinodiwa kupfuudza muedzo zvakare uye kushanyira endocrinologist. Izvo zvakawanda zve thyrotropin zvine ngozi kumwana uye kazhinji zvinokonzera zvinetso zvekuita gumbo, zvichimisa kufambiswa kwema embryo nekusava nemasimba. Kuti kuenzanise hutachiwana hweTSH muvakadzi vanogadzirira kuberekwa, mishonga inokosha inorayirwa:
- levothyroxine sodium;
- Bagotiroks;
- L-thyroxine;
- Tiro-4;
- L-Tirok uye zvakafanana.