Zvinonyatsozivikanwa kuti vanhu vane hypertension kwenguva yakareba vari pangozi yakawanda ye myocardial infarction, stroke, kuchinja mumidziyo ye fundus uye kusagadzikana kwechirwere chisingaperi. Nokudaro, varwere vane kuwedzera kwekuwedzera kweropa, vanoratidza kushandiswa kwemishonga inopesana nemishonga. Maererano nezvidzidzo zvekuchiremba, rimwe remishonga inoshanda uye yakachengeteka yezvinomanikidza mapiritsi Lizinopril.
Zviratidzo zvekushandiswa kwemapiritsi Lizinopril
Chirwere ichi chinokurudzirwa munyaya dzinotevera:
- Arterial hypertension (sechiremera chekuchengetedza mishonga kana kuti pamwe chete nemamwe mishonga inorwisa mishonga);
- chisingaperi chinokanganisa mwoyo (mune pamwe chete kurapwa kwevarwere vanotora mwoyo glycosides uye diuretics);
- acute myocardial infarction (kutanga kurapwa pazuva rokutanga kune varwere vane hukama hwakasimba hwemahemodynamic kuchengetedza izvi zviyero, pamwe nekudzivirira kwekusiya ventricular kusagadzikana nekushaya mwoyo);
- chirwere cheshuga nephropathy (a decrease in albuminuria kune varwere vane chirwere chechirwere cheshuga chinokonzerwa nehutano hweropa uye nevarwere vane chirwere cheshuga chechipiri ane ropa rakanyanya).
Kuumbwa uye pharmacological action ye lisinopril
Nhengo inoshanda yechirwere ichi lisinopril dihydrate. Zvinhu zvinobatsira ndezvi: lactose, starch, silicon dioxide colloid, talc, magnesium stearate, nezvimwewo. Lizinopril inosunungurwa mumapwendefa e5, 10 uye 20 mg.
Mishonga iyi ndeyekirasi ye inhibitors ye-angiotensin-kuchinja enzyme (ACE inhibitors). Inopa cardioprotective (inogadzirisa chinoshanda chemuyocardium), vasodilator uye natriuretic (inobvisa marashi e-sodium nemuji).
Nhamba ye lisinopril
Maererano nemirairo yekushandiswa, mahwendefa e lisinopril anotorwa kamwe chete pazuva, pasinei nokuti zvokudya zvinowanikwa sei. Zvinokurudzirwa kutora mushonga panguva imwechete (zvichida mangwanani).
Nhamba inobva mukurudzi rwehutano uye inogona kutsanangurwa pachavo nechiremba anoshanda. Saka, neArterial hypertension, chiyero chekutanga chemazuva ose, sekutonga, chinonzi 10 mg, uye chirwere chekuchengetedza chiri 20 mg. Maziro ezuva nezuva haafaniri kudarika 40 mg. Kana kutora Lisinopril pamwero wakanyanya hausi kupa zvinodiwa, zvinokwanisika kupa mimwe mishonga.
Precautions
Kupindirana kwekushandiswa kwe lisinopril:
- hereditary idiopathic edema, Quincke's edema ;
- angioedema munhoroondo;
- mimba uye lactation;
- kusagamuchirwa kwomumwe munhu wezvinodhaka zvikamu.
Nekuchenjera, mushonga uyu unorayirwa mumatambudziko anotevera:
- ischemic heart disease;
- coronary insufficiency;
- zvirwere zvinokanganisa;
- collagenoses (kusanganisira systemic lupus erythematosus, scleroderma);
- hyperkalemia kana ngozi yakawedzerwa yekuitika kwayo (nechirwere cheshuga, kushandiswa panguva imwechete ye diuretics, kukundikana kukuru kwetsvina);
- hyponatremia kana sodium inogadziriswa muzvokudya;
- hyperuricemia;
- kutemwa kweiyo mafungiro ekuchinja;
- kukwegura, nezvimwewo.
Zvikanganiso zve lisinopril:
- musoro, chizoro;
- kushushikana kwehope;
- tachycardia;
- cardiac arrhythmia;
- hypotension;
- kuderedza hemoglobin uye hematocrit;
- chifuva;
- kushungurudza, kurutsa;
- diarrhea;
- akaremara renal basa;
- kuputika kweganda, nezvimwewo.
Penguva yekurapa ne lisinopril vanofanira nguva nenguva kutarisa chiropa basa, potasium nemamwe electrolytes muropa serum, kliniki yeropa.