Turner's syndrome kana kuti Turner-Shereshevsky syndrome chirwere chisina kujairika chinokonzerwa nehutachiona hwe X chromosomes uye inowanikwa chete muvakadzi. Mhuri yezviratidzo zvehutano huno maererano naShershevsky yaisanganisira kugadzirisa zvepabonde, ganda repterygoid rinoputika pamutsipa uye kuora kwehutano hwehuta. Vakadzi vanotambura neT Turner syndrome vanowanzotambura uye vasina simba .
Shereshevsky-Turner Syndrome - zvikonzero
Sezvo mutemo, ye-Y-chromosome yakagadzirwa nemurume inosvika 46 (23 pairs) yemakromosomes. Pakati idzi, rimwe boka rinosanganisira chromosomes zvepabonde (XX muvakadzi kana XY mune varume). Mune nyaya ye Turner's Syndrome, imwe yeviri ye-X-chromosome inoshayikwa zvachose kana kukuvara. Ndeipi chaiyo iyo inokonzerwa nehutachiona hunokonzera kuti Turner's syndrome isanyatsogadziriswa, sezvo zvazvo chirwere chacho chichizviratidza pachipatara chekubata mwana, hachisi nhaka.
Kuvapo kwechirwere kunosimbiswa nekuongorora karyotype, kureva, tsanangudzo yeiyo genetic yekromosomes. Izvozvo zvinotevera chromosomal zvisiri izvo zvinogona kuonekwa:
- Chikoro karyotype yeT Turner syndrome ndeye 45X, ndiko kuti, kusakwana kwakakwana kwei X chromosome. Ichi karyotype inowanikwa mune vanopfuura 50% yevarwere, uye mu80% yemhosva hapana baba vane chromosome yababa.
- Mosaic - kureva, kukanganisa kune imwechete kana kuti mamwe ma chromosomes mumutauro wemhando.
- Kurongeka kwemashure kweimwe yei X chromosomes: iyo annular X chromosome, kurasikirwa kwekromosome yenguva shoma kana yakareba.
Syndrome Shereshevsky-Turner - zviratidzo
Kakawanda kunonoka kukura mumuviri kunoratidzika kunyange pakuberekwa - iyi inenge yakareba kureba uye kuyerwa kwechecheche, zvinogonawo kukonzera majoo ejoka (iyo inogadzirisa mukati), kupfugama kwetsoka nemichindwe, uye kuvapo kweganda re pterygoid pamutsipa.
Kana Turner's syndrome isingawanikwi nguva pfupi mushure mekuberekwa, zvino gare gare inozviratidza nenzira yezvinotevera zviratidzo zviratidzo:
- kukura kwekukurumidza, kazhinji kukura kwekukura kunodonha zvakanyanyisa mushure memakore matatu;
- chamfered lowered chin;
- mutsipa wakareba mutsva, kazhinji nemapanga ehwehwe;
- rutsoka rutsvuku rwevhudzi kukura munharaunda ye occipital;
- bhokisi rakapararira rakaparadzaniswa zvakanyanya, dzimwe nguva zvipembenene zvakaoma;
- kuputika uye kusagadzikana kwechimiro chechirwere, chirwere chekunzwa kazhinji;
- kunonoka pakupera;
- mazamu asina kufanira muhutano (anenge makore gumi nematanhatu);
- kusavapo kwekuenda kumwedzi.
Inenge 90% yevasikana vane Turner's syndrome vane uterus uye mavhai evanhu vasati vashandurwa, uye ivo vasina simba kunyange nekurapa panguva yakakodzera uye hormonal therapy inobatsira kubvisa kunonoka pakukura mumuviri.
Kusara kwekuvandudzwa kwepfungwa hakuwanzoonekwi, kunyange kunyanya kushaya dambudziko kunokwanisika uye, kazhinji zvisingaiti, zvimwe zvinetso zvinosangana nekuziva sciences chaiyo inoda kunyanya kutarisirwa.
Syndrome Shereshevsky-Turner - kurapwa
Chinangwa chikuru chekurapa muhupo hweTranser's syndrome ndechekuita kuti huwandu huri kukura uye kuyanana kwepabonde kwemusikana . Icho chiremba chirwere chacho chinowanikwa uye kurapwa kwakatanga, mukana wakawanda wekuvandudzwa kwechirwere chechiremba.
Nokuda kweizvi, kutanga, hormone therapy inoshandiswa, uye nezera rekuyaruka, hormone yevakadzi, isrogen, inowedzerwa nayo.
Mushure mokuzadzisa hupombwe, kusanganiswa kwehomoni kushandiswa kwetachiona kana estrogen uye progestin therapy inoitwa.
Pasinei nekuti panguva yekurapa varwere vanogona kukura zvakajeka uye vanotungamirira hupenyu hwepabonde hunowanzoitika, ivo vanowanzoshaya zvibereko. Kukwanisa kubereka mwana nekushandiswa kwehutano hwakakosha kunowanikwa mu10% chete yevakadzi vane chirwere che Turner's syndrome, uye ipapo nekaryotype mumhando yemhando.