Prolactin imwe yemakiromoni anokosha zvikuru mumuviri wechikadzi. Kubva pane chokwadi, mune zvakakanganiswa zvinoshandiswa, zvisinei nokuti zvarinotaura zvinowirirana nenzira yakarongeka, zvizhinji zvehutano hunoenderana. Ngationgororei zvakadzama, chii chinokonzera prolactin, chimiro chevakadzi kuburikidza nemakore (tafura), iyo inoratidzirwa nekukanganisa kubva kune zvakasikwa.
Chii chinonzi prolactin chinotarisirwa?
Iyi hormone, yemhuri yeprotectin-yakafanana nemapuroteni, inobudiswa neuropi - munzvimbo yakatarisa yepituitary gland. Mukuwedzera, muchikamu chechikamu chayo chinobatanidza dzimwe nhengo: mammary glands, placenta, chirwere chendaneti, zvirwere zvemuviri. Muropa rega, prolactin inopararira nenzira dzakasiyana-siyana, yakasiyana mu molecular weight. Chimwe chikamu chikuru chinokonzerwa nehuwandu hweprolactin nechechi maserosi, iyo inoshanda zvikuru.
Zviratidzo zveprolactin zvinotarwa nemazana emhando dzakasiyana uye zviito. Ngatitangei mabasa ayo makuru mumukadzikadzi:
- kuumbwa kwechipiri chepabonde maitiro pazera remakore;
- chirevo chekugadzirwa kwemukaka nemasikirwe emakumbo mushure mekusununguka;
- kudzivirira kubata pamuviri panguva yekuvhunga;
- kuderedza kurwadziwa kwekunzwa;
- kutsigira kushanda kwemuviri wemiviri unobudisa progesterone;
- kukurudzira kusimwa kwe follicle uye ovulation;
- mutemo wemvura-electrolyte;
- kushandiswa kwemagetsi ekugadzirisa;
- enrichment of bone tissue with calcium;
- kukurudzira kwekukura kwemidziyo mutsva yeropa;
- kuumbwa kwemazuva ekuberekwa;
- kukura kwekuita zvepabonde, nezvimwewo.
Prolactin analysis
Mukati yehutachiona hwehutachiona hutori husina kugadziriswa, vanhu vazhinji vane mubvunzo wekutora Prolactin. Kazhinji, mutungamiri wekudzidza kwakadaro unopiwa neGynecologist-endocrinologist pamberi pekunyunyuta, izvo zvinogona kubatanidzwa nekuputsa kwekushandiswa kwezvinhu zvinoshandiswa zvehupenyu zviri kuongororwa. Saka, kazhinji ropa rinopiwa nokuda kweprolactin mukana wekufamba, kusununguka kusina kujairika kubva kumawere, kuve kurepo kwekuita pamuviri, kukura kwevhu pane chiso, zvinetso zveganda, nezvimwewo.
Kuti uwane mugumisiro wakavimbika, haufaniri kungozvifunga chete pazuva rekushandura kupa prolactin, asi chengeta mamwe mimwe mitemo uye ita maitiro ekugadzirira. Mitemo mikuru yekutsvakurudza iyi hormone ndeyotevera:
- Shanduro yeropa inoshandiswa musi wa5: 3-5 zuva rekuenda kumwedzi;
- Muenzaniso wacho unotorwa kubva mumhino yeinnar musina chinhu chisina chinhu mangwanani, maawa matatu mushure mekumuka;
- zuva rakasati rasvika chidzidzo chacho chisina kushanyira sauna, gungwa, kutora kushambaira kunopisa, kutengesa, kurara kwepabonde, kuita basa;
- manheru ezvokudya zvinodiwa, kusanganisa kudya kwakakwana, kuvhara mapuroteni uye kubvisa doro;
- kusati kwatora ropa kunofanira kukanganisirwa kunetseka kwepfungwa;
- Mambakwedza isati yasvika, haugoni kusvuta uye kushanda panzvimbo yemukomana.
Pamusana pekuwedzera kwekunzwa kwehuwandu hwehomoni iyi kune vazhinji vari kunze nekunze kwemaitiro, kuitira kuti tisaita zviratidzo zvisina kururama, nyanzvi dzakawanda dzinokurudzira kupa ropa kuti ridzidze katatu pamwedzi imwe neimwe. Migumisiro inozozivikanwa mukati mezuva rimwe, uye chiremba anofanira kududzira zviratidzo uye kuita kuti kuongororwa.
Prolactin - chimiro chevakadzi (tafura)
Iyo inowanzochengetedzwa kweprolactin muropa inowirirana zvichienderana nezera, chiyero cheesrogen chinobudiswa, kuberekwa, nguva yekuyamwisa, etc. Kuita kuti zvive nyore kwazvo kududzira mhinduro yehutoni hweprolactini mukati mevakadzi, tafura ine chimiro nemakore inonyatsodzorera tsika dzekutarisa.
Nguva yezera | Kazhinji chiitiko, md / l |
vana vachangoberekwa | 1700-2000 |
kusvika kune 1 gore | 630 |
1-10 makore | 40-400 |
11-16 ane makore | 40-600 |
16-45 makore (kuberekwa kwezera) | 40-600 |
45 uyezve (kumisa mimba) | 25-400 |
Sezvo zvinogona kuonekwa kubva patafura, maererano nehutachiona hwehomoni prolactin, chimiro chevakadzi chichienderana nezera mushure mekupera uye asati asvika kumwedzi. Inofanira kutarirwa mupfungwa kuti kuchinja kwezuva nezuva kunobvumirwa, zvichienderana nehope, kudya, kushushikana, kuita zvepabonde, zvinotonhora, nezvimwewo. Mukuwedzera, kubatana kwechinhu ichi hachisi chakafanana muzvikamu zvakasiyana zvekuenda kumwedzi. Izvi zvinofunga nezvemitemo yekugadzirira kuongorora.
Prolactin mukudzivirira inowanzoitika
Prolactin, chiyero apo vakadzi vari kubereka mwana kuchinjwa nekuda kwehutano hwakawanda huri mumuviri, hunotanga kuwedzera zvishoma nezvishoma mumutambo wekutanga uye huri kuramba hukwiridzirwa kusvika panguva yekuberekwa (mazuva mashomanana asati aberekwa, zvishoma nezvishoma zvinoderera). Muchiitiko ichi, tafura inotevera inoshandiswa, apo tsika yeprolactin muvakadzi inoratidzirwa kwete nezera, asi nenguva yekuzvitakura.
Nguva yekubereka mwana | Kazhinji chiitiko, md / l |
8-12 mavhiki | 500-2000 |
13-27 mavhiki | 2000-6000 |
kubvira masvondo makumi maviri | 4000-10000 |
Kuongororwa kweprolactin mukudzivirira hakuwanzogadziriswa, uye nyanzvi dzakawanda dzinofunga kuti hazvina zvidzidzo, nekuda kwekusiyana kukuru pakati pemigumisiro yakazara. Kana kudiwa kwakadaro kunomuka, saka sechimiro vanotungamirirwa nekukosha kwe 10000 mU / l, iyo isingafaniri kudarika, kana zvose zviri mumuviri wemukadzi nevana remangwana zviri kufamba zvakanaka.
Prolactinum pamakemikemia - chimiro kana chiyero
Mushure mokuberekwa, uwandu hweprolactin hunoenderana nerudzi rwekuyamwisa. Muchiitiko chacho apo pane kugadzirwa kwekugadzira pasina kushandisa mazamu, zvishoma nezvishoma kuwanda kwei hormone yakagadzirirwa kusvika pamatanho e 400-600 mU / l. Kana mukadzi ari kuyamwa, kakawanda mwana anoyamwa, inowedzera muzinga. Itafura inotevera ichakutaurira huwandu hwemahomoni eprolactin (zvinowanzoitika, zvichienderana nenguva yekudya).
Lactation period | Kazhinji chiitiko, md / l |
kutanga mwedzi mitanhatu | 2500 |
Mwedzi 7-12 | 1000-1200 |
kubva pamwedzi gumi nemaviri | 600-1000 |
Prolactin pakuguma kwemazuva ndeyezvakanaka kune vakadzi
Mushure mekupera kwekupedzisira kwemwedzi, apo huwandu hwemashure ehutori huri kuitika huri mumuviri wevakadzi, huwandu hweprolactin, hwakafanana nemamwe mahomoni, hunotanga kuderera. Pakati pevhesi, tsika dzayo muzera iri dzinotangira kubva pa25 kusvika ku 400 mU / L (data ine tefura - prolactin, inowanzoita vakadzi nezera). Gore roga roga izvi zvinokosha zvinoramba zvichidzika.
Hyperprolactinemia muvakadzi - chii ichocho?
Kana kuongorora kuchiratidza kuti prolactin yakakwirira mumukadzi, asi iye asina pamuviri, haafaniri kudya, kushandiswa kweropa rose kunosangana (kureva, maitiro ehupenyu ekuwedzerwa kushandiswa kwayo haasi kuonekwa), munhu anofanira kutarisa chinokonzera mukurapa. Izvi zvinonzi hyperprolactinemia uye mumatambudziko akawanda zvinoda kuchinjwa.
Zvinokonzera kuwedzera prolactin
High prolactin inogona kukonzerwa nemapoka matatu emakonzera:
1. Organic:
- matumbo emucheka wepituitary (prolactinoma, adenoma, meningioma, etc.);
- matumbo e hypothalamus (glioma, germinoma, etc.);
- cysts dzeuropi;
- arteriovenous defects ye hypothalamus;
- irradiation ye hypothalamic region;
- chirwere chekucheka kwegumbo remuviri wepituitary, nezvimwewo.
2. Kushanda:
- chirwere chechiropa;
- primary hypothyroidism;
- polycystic ovary;
- systemic lupus erythematosus;
- chisingakoshi renal failure;
- kusakwanira kwe adrenal cortex;
- kuporesa kushandiswa mumutsara;
- shingles, nezvimwewo.
3. Zvemishonga - kushandisa zvinodhaka:
- antiemetics;
- antipsychotics;
- isrogen rine mazano;
- antihistamines;
- vanopikisa calcium , nezvimwewo.
Hyperprolactinaemia muvakadzi - zviratidzo
Kuwedzera kweprolactin kunowanzosangana nemakiriniki anotevera:
- kusununguka kubva kumaronda emammary;
- kurwadziwa muzvinyoro zvinyoro;
- zvisimbiso mubhokisi;
- kuoma kwemudzimai ;
- kusagadzikana kwekuenda kumwedzi;
- kazhinji misoro;
- kuora kwekuziva;
- kuora kwemaonero;
- overweight;
- kuderedza libido;
- seborrhea wepachipi ;
- acne;
- kukura kwakanyanya kwebvudzi pamuviri;
- kurara kunokanganisa, nezvimwewo.
Hyperprolactinemia muvakadzi - kurapwa
Kana migumisiro yechirwere chekuisira ropa inogadzira hyperprolactinemia kuvakadzi, nepo pane zviratidzo zvisina kunaka, kuratidza kutyisa mararamiro, humwe hutano hwekuongorora hunokurudzirwa, pakati pawo:
- miedzo yehomoni yekemikari, mahomoni ezvepabonde;
- biochemical blood test;
- Ultrasound ye thyroid gland , nhengo dzomukati, mimba yemimba;
- magnetic resonance kana kuti computed tomography yeuropi.
Kurapa kunobva pane zvakaonekwa kusakanganisika. Muchiitiko chekucherechedza kwemaoplasms europi, kurapwa kwekuvhiya, kazhinji kunosanganiswa ne radiotherapy, kunogona kunyorwa. Mune dzimwe nguva, nzira huru yekurapa inoshandiswa mishonga, inotarirwa kubvisa chinokonzera. Mukuwedzera, zvakananga kuderedza kusanganiswa kwei hormone, dopaminomimetic zvinodhaka (Bromocriptine, Kabergolin, nezvimwewo) inogona kurongerwa.
Yakaderedza prolactin
Low prolactin haifaniri kuderera, uye zvinowanzokonzera zvinotevera:
- kubata nguva isati yasvika;
- postpartum infarction ye gland pituitary;
- kutora mamwe mishonga (anticonvulsants, dopaminergic drugs, nezvimwewo).