Glucocorticosteroid mahomoni ndiwo chikamu chinokosha chemishonga inorapwa mukurapa zvirwere zvakawanda zvinotungamirirwa nekuputira maitiro. Kusanganisira Dexamethasone - majekiseni emudhaka uyu anoshanda zvikuru uye panguva imwechete yakachengeteka. Mukuenzanisa nedzimwe glucocorticosteroids, mutengesi uyu anokonzera zvishoma madhara.
Pharmacological features ye injection yemishonga Dexamethasone
Iyo inofungidzirwa hormonal agent inobatanidza zvitatu zvikuru pamutumbi:
- anti-inflammatory;
- immunosuppressive;
- antiallergic.
Mukuwedzera, sarudzo yeDexamethasone inoderedza edema yemakamu membrane emuitiro wekupemha, izvo zvinodiwa mukurapa kwekuvhara maitiro mubronchi, uye kunoderedzawo kutaridzika kwechakavanzika chakavanzika, kuita kuti zvinyorwa zvayo panguva yekukanganiswa.
Chii chinonzi injection yeDexamethasone?
Kutanga, zvose zvinoshandiswa nemishonga zvinoshandiswa muHodmone replacement therapy yezvirwere zve endocrine:
- congenital hypoplasia ye adrenal cortex;
- Chirwere cheAdisonison;
- kusagadzikana kwakanyanya kweadrenal cortex, zvose zvakakosha uye yechipiri;
- acute uye subacute thyroiditis;
- adrenogenital syndrome;
- tumor hypercalcemia;
- hypothyroidism.
Zviratidzo zvinosara zvekushandiswa kweDexamethasone injections:
1. Mamiriro akaoma:
- postoperative;
- shure-kunetsa;
- kuwedzerwa ropa;
- cardiogenic;
- kupisa;
- toxic.
2. Pathology yomuviri wekupemha:
- chimiro chechifu;
- kutapukisa-inokonzerwa nehutachiona hwechirwere;
- sarcoidosis ;
- kuwedzera kwechirwere chisingaperi chisingaoneki;
- severe bronchospasm;
- Chirwere cheLeffler;
- kuparadzira chirwere chetachiona;
- berylliosis.
3. Cerebral edema ne:
- craniocerebral trauma;
- hemorrhages;
- matumbo;
- encephalitis;
- neurosurgical operation;
- kuora kwemavara emapapu;
- meningitis.
4. Zvirwere zveRheumatic:
- acute rheumatic heart disease;
- rheumatoid arthritis panguva yekuwedzera;
- kuparadzirwa lupus erythematosus.
5. Anemia:
- idiopathic;
- autoimmune;
- congenital;
- erythroblastopenia;
- hemolytic;
- hypoplastic.
6. Zvirwere zvekugadzira muviri:
- hepatitis;
- nephrotic syndrome;
- nonspecific ulcerative colitis.
7. Dhigenerative uye kuvhiringidza maitiro muzvibatanidza nemisungo:
- tenosynovitis;
- epicondylitis;
- arthritis;
- bursitis;
- osteochondrosis;
- styloidite;
- Chirwere cheBechterew;
- osteoarthritis;
- myositis.
8. Zvirwere zveropa:
- secondary thrombocytopenia;
- lymphomas;
- lymphocytic leukemia;
- idiopathic thrombocytopenic purpura;
- leukemia;
- plasmacytoma;
- agranulocytosis.
9. Ophthalmic pathologies:
- keratitis;
- irit;
- conjunctivitis;
- blepharitis;
- iridocyclitis ;
- keratoconjunctivitis;
- sclerite;
- kunzwira tsitsi ophthalmia;
- blepharoconjunctivitis;
- episcleritis;
- kuvhiringidzika mushure mokushanda mumaziso.
10. Zvivara zveganda:
- red discoid lupus erythematosus;
- keloids;
- annular granuloma;
- acute severe dermatosis.
Dexamethasone injections inorayirwawo kuti zvive zvechirwere, zvirwere zve-systemic zvezvibatanidza zvisikwa uye zvirwere zvakakomba. Muchikamu chekupedzisira, mishonga yehomoni inosanganiswa nemishonga inorwisa mabhakitiriya.
Nzira yekugadzira sei Dexamethasone?
Muchiitiko chinokurumidza uye chakakomba, injirusi inoputira iyi yemishonga inopiwa muyero ye 4-20 mg (zvichienderana nehutachiona hwezvirwere) kusvikira 4 kana pazuva. Iyo jekiseni inofanira kuitwa zvishoma nezvishoma, kwekanguva 1 miniti.
Kana hutano hwehutano hunogutsa, mushonga unofanirwa kutarisirwa kuiswa mumutambo wakafanana.
Nzira yekurapa kwakadaro mazuva 3-4, kuchengetedza chirwere mushure mokubvisa kuwedzera - 0.2-9 mg kwemaawa 24. Kana kuwedzera kurapwa kwakakosha, enda kuDexamethasone mune mahwendefa.
Dzimwe nguva majekesiti anonzi intra-articular uye interstitial anorayirwa. Mumamiriro ezvinhu akadaro, chiitiko chezuva nezuva chemishonga yeHodmonal is 0.2-6 mg.
Contraindications uye nemigumisiro yejojo ​​Dexamethasone
Zvirwere uye mamiriro ezvinhu ayo sarudzo yakatsanangurwa haigone kushandiswa:
- glaucoma;
- zvipembenene zvinotapukira zve periarticular tishu nemajoints;
- hypersensitivity;
- amoebic infections;
- chimiro chinoshanda chechifuba;
- systemic mycosis;
- acute purulent ocular infections;
- nguva uye mushure mekudzivirira.
Kana zviri zvemigumisiro, Dexamethasone, sekutonga, inobvumirwa zvakanaka. Muzviitiko zvisingawanzoitiki, pane zvinetso zvisingabatsiri kubva kune zvinotevera masimba emuviri:
- digestive;
- mwoyo;
- endocrine;
- kutya;
- musculoskeletal;
- immune.
Dzimwe nguva ganda uye kugarisana kwemukati zvinowanikwa, calcium metabolism, maonero ezvimwe nhengo dzemuviri dzinovhiringidzika.