Mukuputika ne pathogen isingazivikanwi kana kuti yakakanganiswa zvirwere (microbes, fungus), zvinodhaka pamwe chete nezvakawanda zvikuru zvingaita basa rinodiwa. 5-NOC inorwisa antibacterial agent inopesana nemakiromita akawanda anozivikanwa. Izvo zvinobudirira kupikisa dzimwe mycoses.
5-NOC - kuumbwa
Chinhu chikuru chechirwere ichi chiri mubvunzo ndi nitroxoline. Icho chemakemikari yakabva kune 8-hydroxyquinoline, inhibitisa kushandiswa kweDNA kubva mumasero epathogenic uye inodzivirira kubereka kwavo. Izvo zvikamu zvinobatsira zvinowanikwa mu 5-NOC-tablet yekugadzirisa zvinosanganisira:
- lactose monohydrate;
- calcium hydrogen phosphate;
- corn starch;
- Povidone K25;
- colloidal silicon dioxide;
- akacheneswa talc;
- magnesium stearate;
- crospovidone.
Mapiritsi anobudiswa muhombodo yekudzivirira, iyo inosanganisira zvinhu zvinotevera:
- carmellose sodium;
- acacia gum;
- colloidal silicon dioxide;
- Povidone K25;
- titanium dioxide;
- corn starch;
- sucrose;
- akacheneswa talc;
- calcium carbonate;
- Zvokudya mavara - yellow "Sunset Sunset" (E110) uye quinoline (E104).
5-NOC - kuratidza
Chirwere ichi chinoshandiswa pakurapa zvirwere zvakakomba kana zvishoma nezvishoma zvehutano uye hutano hwekubereka. Matetetsi 5-NOC yakagadzirisa kupesana nemapoka emakiromita:
- Gram-positive aerobic uye anaerobic;
- gram-negative aerobic uye anaerobic;
- mycoplasma ;
- ureaplasma ;
- Trichomonas;
- Mycobacterium tuberculosis;
- dermatophytes;
- mold fungi;
- candidate;
- Zvirwere zvinokonzera kukanganisa zvinopisa uye zvakanyanya mycoses.
5-NOC - zviratidzo zvekushandiswa:
- cystitis;
- pyelonephritis ;
- epididymitis;
- urethritis;
- ane chirwere chetachiona (adenoma, carcinoma) yeprostate;
- prostatitis;
- kuvhiringidza maitiro mubhupa kana chekubuda.
Iyo yakatsanangurwa kugadzirira inoshandiswa kudzivirira utachiona mumamiriro ezvinhu akadaro:
- postoperative period;
- kuongororwa kugadzirisa;
- cystoscopy ;
- catheterization.
5-NOC - migumisiro
Simba rinorwisa antibacterial medication rinogona kukanganisa kusateerera kwemuviri kubva kune chero nzira. Izvi zvinoreva kuti kazhinji haisi kutungamirira kumagumisiro. Muzviitiko zvakasiyana-siyana, kugadzirira 5-NOC kunokonzera:
- tachycardia;
- kurutsa;
- anorexia;
- nausea;
- akashaya chiropa basa;
- chizoro;
- optic neuritis (nekugamuchirwa kwenguva refu);
- paresthesia;
- kusava nekubatana;
- headaches;
- polyneuropathy;
- thrombocytopenia;
- kuwedzera kuwanda kweuric acid;
- urticaria;
- kunhuwa kweganda;
- ataxia;
- kusvibisa urini muhupfumi huri ruvara.
5-NOC zvinopesana
Ichi chishandiso hachina kukurudzirwa kune mumwe munhu kusagamuchirwa kune chimwe chezvinhu zvinongororwa pamusoro apa, kusanganisira maidiki emakemikari nemagetsi. Iro-5-NOC zvinodhaka zvinopesana nemamiriro ezvinhu akadaro:
- pamuviri;
- cataract;
- kunwisa;
- kukanganiswa kwakanyanya kwechiropa kana zveputsvo nechisimba chekusika chinodarika 20 ml / min (yakatemwa kazhinji, nokungwarira);
- ava nemakore matatu.
Nzira yekutora mahwendefa mashanu-NOC?
Mugove wezuva nezuva wemishonga unoenderana nezera uye kuvapo kwemamwe zvirwere zvisingaperi. Vanhu vakuru pazuva vanoda 400 mg yemishonga 5-NOC - chikumbiro chinosanganisira kutora chiringo ichi, chakaparadzaniswa kanomwe, 100 mg (mapiritsi maviri) vasati vadya. Nechiremera chakasimba chebhakitiriya, chikamu chakawedzerwa (800 mg). Vana vane makore anopfuura mashanu vanorayirwa 200-400 mg yemishonga nguva dzose maawa makumi maviri nemaviri, uye vana vane makore 3-5 - 200 mg. Dzidzo yehutachiona haipfuuri mavhiki maviri-4, kana zvichidikanwa, idzoke zvakare.
Neine renal and hepatic insufficiency, 5-NOC inoshandiswa nekunonoka kukuru - zviratidzo zvekushandiswa hazvirevi zvirwere izvi, asi mukurwara kwakakomba, mishonga inorwisa mabhakitiriya inogona kurongerwa. Muzviitiko izvi, tora 1 bhetani 1 kana kane pazuva. Zvinotarisirwa kuongorora nguva dzose maitiro ehuputi uye chiropa kune kurapwa uye kuongorora huwandu hwekuvhenekera kwekusika.
5-NOC - chikwata che cystitis
Nhamba yeantimicrobial agent inowirirana neyero yakazara ye 400 mg nitroxoline maawa makumi mana nemaviri. 5-NOC ne cystitis inokurudzirwa kwemazuva 10-21. Nguva chaiyo yehutano inotarirwa neurorosi inotarisana neongororo yebhroatori, kuoma kwekuvhiringidza, uye kuvapo kwemigumisiro kubva mukurapa. Dzimwe nguva inofanira kuendeswa kumwedzi mumwe chete, kunyanya kana utachiona hwakabatanidzwa kana yechipiri.
5-NOC ne pyelonephritis
Iyo inorondedzwa kurwara mufomu yakaoma inoda kosi pfupi yemishonga inorwisa mabhakitiriya, 400 mg zuva rimwe nerimwe kwevhiki 2-2.5. Muchiitiko chisingaperi cheperionephritis inogara ichidzoka, urologist inosarudza kuti ingatora sei 5-NOC. Pane zvirongwa zvekurapa kwenguva refu (2-3 mwedzi kwemazuva gumi nemana) uye zvinyorwa zvine kushandiswa kwenguva refu kwechirwere mumutengo wakaderera (100-200 mg).
Dzimwe nguva zvinotora kugamuchirwa kwenguva refu kwe5-NOC - zviratidzo zvekushandiswa zvinosanganisira maitiro akaoma epielonephritis:
- xanthogranulomatous;
- purulent;
- kuverenga.
5-NOC pakuberekwa
Munharaunda yose yekupera kwegore, chirwere chemudzimai chirwere chinonyanya kuoma uye chinogona kuvhiringidza. Nemhaka yeizvi, vanaamai vanotarisira kazhinji vanofarira 5-NOC - ndinogona kunwa iyo panguva yekuzvitakura uye mune zvipi zvidha. Iyi mishonga inorwisa mabhakitiriya inopesana nemamiriro ezvinhu aya, nokuti inogona kukanganisa kukura kana kuumbwa kwe fetus.
5-NOC zvakafanana
Apo iyo yakaratidza mishonga inorwisa mishonga inogona kushandiswa kana inokonzera migumisiro yakakomba, inofanira kubviswa. Nzira chete yekugadziridza mahwendefa mashanu-NOC ndeyokushandisa zvakafanana zvakafananidza kana ma generic. Kune zvirevo zviviri zvakananga kune zvinotsanangurwa nemishonga:
- Nitroxoline (Germany, Russia);
- Uroksolin (Ukraine).
Mushonga wokutanga unogadzirwa nehutano hwakasiyana hwezvigadzirwa zvinoshandiswa, izvo zvinokodzera kurapwa nepamusoro dheji. Chirwere chechipiri chinongowanikwa mumapiritsi nemaikemikari anoshanda ane 50 mg. Kana kusawirirana kune nitroxoline kana zvigadzirwa zvayo zvinoonekwa, zvakakosha kushandisa generic. Iyi mishonga inenge yakangofanana nemafanana ne 5-NOC - zviratidzo zvikuru zvekushandiswa, antibacterial uye antifungal basa, asi yakasiyana. Mishonga inobatsira inowanikwa nenzira yebhakteriophages:
- dysentery polyvalent;
- intesties;
- kana;
- staphylococcal;
- Protein;
- Klebsiella pneumonia;
- Pseudomonas (pseudomonas);
- kolik-proteyny;
- salmonella.
Zvimwe zvidimbu zvine zviratidzo zvakafanana:
- Fosmicin;
- Ureacid;
- Fosmural;
- Bernie;
- Fosmicin;
- Monural;
- Phosphoral;
- Urophosfabol;
- Cystoral;
- Forterase;
- Urofoscin;
- Phosphocin;
- Espa-Focine.